Computer Simulation and Data Analysis in Molecular Biology and Biophysics

An Introduction Using R
2009
ISBN: 978-1-4419-0084-5
Verlag: Springer

Buch, Englisch, 321 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 738 g

Reihe: Biological and Medical Physics, Biomedical Engineering

This book provides an introduction to two important aspects of modern bioch- istry, molecular biology, and biophysics: computer simulation and data analysis. My aim is to introduce the tools that will enable students to learn and use some f- damental methods to construct quantitative models of biological mechanisms, both deterministicandwithsomeelementsofrandomness;tolearnhowconceptsofpr- ability can help to understand important features of DNA sequences; and to apply a useful set of statistical methods to analysis of experimental data. The availability of very capable but inexpensive personal computers and software makes it possible to do such work at a much higher level, but in a much easier way, than ever before. TheExecutiveSummaryofthein?uential2003reportfromtheNationalAcademy of Sciences, “BIO 2010: Transforming Undergraduate Education for Future - search Biologists” [12], begins The interplay of the recombinant DNA, instrumentation, and digital revolutions has p- foundly transformed biological research. The con?uence of these three innovations has led to important discoveries, such as the mapping of the human genome. How biologists design, perform, and analyze experiments is changing swiftly. Biological concepts and models are becoming more quantitative, and biological research has become critically dependent on concepts and methods drawn from other scienti?c disciplines. The connections between the biological sciences and the physical sciences, mathematics, and computer science are rapidly becoming deeper and more extensive.

Zielgruppe

Research

Autoren/Hrsg.

Bloomfield, Victor

Fachgebiete

• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
• Interdisziplinäres Wissenschaften Wissenschaften: Forschung und Information Forschungsmethodik, Wissenschaftliche Ausstattung
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Naturwissenschaften Biowissenschaften Proteinforschung
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Angewandte Biologie Bioinformatik
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Mathematik | Informatik EDV | Informatik Angewandte Informatik Computeranwendungen in Wissenschaft & Technologie
• Mathematik | Informatik EDV | Informatik Angewandte Informatik Bioinformatik
• Technische Wissenschaften Technik Allgemein Computeranwendungen in der Technik
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

The Basics of R.- Calculating with R.- Plotting with R.- Functions and Programming.- Data and Packages.- Simulation of Biological Processes.- Equilibrium and Steady State Calculations.- Differential Equations and Reaction Kinetics.- Population Dynamics.- Diffusion and Transport.- Regulation and Control of Metabolism.- Models of Regulation.- Analyzing DNA and Protein Sequences.- Probability and Population Genetics.- DNA Sequence Analysis.- Statistical Analysis in Molecular and Cellular Biology.- Statistical Analysis of Data.- Microarrays.