Blomhoff Vitamin A in Health and Disease

1. Auflage 1994
ISBN: 978-1-4822-7756-2
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 704 Seiten

Reihe: Antioxidants in Health and Disease

Autoren/Hrsg.

Blomhoff, Rune

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Ernährungsmedizin, Diätetik

Inhaltsverzeichnis

Introduction

Overview of Vitamin A Metabolism and Function

Metabolism of Vitamin A

Absorption of Vitamin A
Role of Perisinusoidal Stellate Cells in Vitamin A Storage
The Retinol-Binding Protein Superfamily
Dynamic and Control of Plasma Retinol
Retinoic Acid Homeostasis: Prospective Roles of b-Carotene, Retinol, CRBP, and CRABP

Mechanism of Action of Vitamin A and Carotenoids

Role of Nuclear Retinoic Acid Receptors in the Regulation of Gene Expression
The Retinoid X Receptors: Modulators of Multiple Hormonal Signaling Pathways
Retinoylation of Proteins in Mammalian Cells
Role of Carotenoids in Antioxidant Defense

Embryonic Development

Role of Retinoids in Embryonic Development
Vitamin A in Lung Development and Bronchopulmonary Dysplasia
Are Ethanol-Induced Birth Defects Caused by Functional Retinoic Acid Deficiency?

Skin and Epithelial Cells

Role of Retinoids in Normal and Diseased Skin
Regulation of Epithelial Differentiation by Retinoids

Blood Cells

Role of Retinoids in Normal Hematopoiesis and the Immune System
Retinoids and Acute Myeloid Leukemia

Vision

Retinoid Isomerization Reactions in the Visual System

Reproduction

Vitamin A Functions in the Reproductive Organs

Intake and Cancer Incidence

Vitamin A and Cancer: Epidemiological Evidence in Humans

Deficiency and Toxicity

Vitamin A Deficiency: Its Epidemiology and Relation to Child Mortality and Morbidity
Teratogenicity of Vitamin A and Retinoids

Requirements

Dietary Vitamin A Requirements