Protein Glycosylation

1998
ISBN: 978-0-7923-8337-6
Verlag: Springer US

Buch, Englisch, 508 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 2020 g

provides clear, up-to-date, and integrated coverage of key topics in this field. Particular emphasis is placed on the biosynthetic pathways that result in a wide variety of identified protein-bound oligosaccharides. begins with an overview of the chemical structures of mono- and oligosaccharides, to provide a scientific basis for the later chapters. The book includes discussions on the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases, as well as a review of the roles of oligosaccharides in glycoprotein function and the in vivo role of glycoproteins themselves. Finally, the in vitro synthesis of glycoproteins is presented, together with future directions in glycobiology.
serves as an excellent text for upper-level undergraduate and graduate students as well as a reference for those scientists whose training is not in glycobiology but who are moving into this field.

Zielgruppe

Research

Autoren/Hrsg.

Bill, Roslyn M.

Wilson, Iain B. H.

Revers, Leigh

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Kosmetische Technologie
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tiergenetik, Reproduktion
• Naturwissenschaften Biowissenschaften Botanik Pflanzenreproduktion, Verbreitung, Genetik
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Proteinforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie

Inhaltsverzeichnis

Sugars and Proteins: Getting it Together.- Sugars and Proteins: Why they Get it Together.- Sugars and Proteins: How they Get it Together.- Core Issues: Building the Groundwork for N-Linked Sugars.- Branching Out: Constructing the Antennae of N-Linked Sugars.- And What About O-Linked Sugars?.- Adding the Finishing Touches: Terminal Elaborations.- Expect the Unexpected: Unfamiliar Glycosylations.- Complementing the Cell: Glycoform Synthesis In Vitro.- Icing on the Cake: Summary and Future Directions.