Bensasson / Land / Truscott Flash Photolysis and Pulse Radiolysis

Contributions to the Chemistry of Biology and Medicine
1. Auflage 2013
ISBN: 978-1-4831-8933-8
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 244 Seiten, Web PDF

Flash Photolysis and Pulse Radiolysis: Contributions to the Chemistry of Biology and Medicine presents the interaction of radiation with biomolecules, which is either beneficial o deleterious to life. This book discusses the biochemical reactions that are not radiation-induced by selectively generating certain types of free radicals present in normal metabolic processes. Organized into nine chapters, this book begins with an overview of the principle of both pulse radiolysis and flash photolysis with photoelectric detection. This text then examines the applications of flash photolysis and pulse radiolysis to the chlorophylls, bile pigments, hemoglobin and myoglobin, and the porphyrins. Other chapters consider the carotenoids related to photosynthesis. This book discusses as well the role of proteins in nearly all biological processes, including enzymatic catalysis, muscular contraction, immune protection, mechanical support, and genetic information. The final chapter deals with the structures and importance of radiosensitizers. This book is a valuable resource for chemists and biochemists.

Autoren/Hrsg.

Bensasson, R. V.

Land, E. J.

Truscott, T. G.

Inhaltsverzeichnis

1;Front Cover;1
2;Flash Photolysis and Pulse Radiolysis: Contributions to the Chemistry of Biology and Medicine;4
3;Copyright Page;5
4;Table of Contents;8
5;Preface;6
6;Chapter 1. Introduction;10
6.1;1.1. FLASH PHOTOLYSIS AND PULSE RADIOLYSIS ;10
6.2;1.2. TRANSIENT SPECIES;11
6.3;1.3. COMPARISON OF EFFECTS OF LIGHT AND IONIZING RADIATIONS\ ;13
6.4;1.4. ASSIGNMENT OF TRANSIENT SPECIES;17
6.5;1.5. PROPERTIES OF EXCITED STATES;20
6.6;1.6. PROPERTIES OF RADICALS;25
6.7;1.7. PROPERTIES OF CARBOCATIONS AND CARBANIONS;27
7;Chapter 2. Tetrapyrrolic Pigments;29
7.1;2.1. THE CHLOROPHYLLS;30
7.2; 2.2. PORPHYRINS RELATED TO HAEM BIOSYNTHESIS;44
7.3;2.3. BILE PIGMENTS;55
7.4;2.4. HAEMOGLOBIN AND MYOGLOBIN;63
8;Chapter 3. Polyenes;76
8.1;3.1. THE C40 CAROTENOIDS AND ANALOGUES;76
8.2;3.3 . SUMMARIZING CONCLUSIONS;100
9;Chapter 4. Proteins and Components;102
9.1;4.1. OCCURRENCE AND IMPORTANCE, STRUCTURE;102
9.2;4.2. GROUND STATE ABSORPTION SPECTRA;103
9.3;4.3. TRIPLET EXCITED STATES OF THE AROMATIC AMINO ACIDS AND AROMATIC PEPTIDES;104
9.4;4.4. EXCITED STATES OF PROTEINS AND ENZYMES;113
9.5;4.5. RADICALS;114
9.6;4.6. SUMMARISING CONCLUSIONS;129
10;Chapter 5. Nucleic Acids and Components;130
10.1;5.1. OCCURRENCE AND IMPORTANCE;130
10.2;5.2. STRUCTURE;130
10.3;5.3. GROUND STATE ABSORPTION SPECTRA;130
10.4;5.4. TRIPLETS OF PYRIMIDINES AND OF THEIR NUCLEOSIDES AND NUCLEOTIDES;132
10.5;5.5. TRIPLETS OF PURINES;137
10.6;5.6. EXCITED STATE REACTIONS OF PYRIMIDINES AND DERIVATIVES IN SOLUTION AND IN DNA;138
10.7;5.7. EXCITED STATE REACTIONS OF PURINES IN SOLUTION AND IN DNA;139
10.8;5.8. TRIPLET EXCLTED STATES OF HYDROCARBON–DNA COMPLEXES;139
10.9;5.9. RADICALS;139
10.10;5.10. SUMMARIZING CONCLUSIONS;143
11;Chapter 6. Electron Transport Chain Components;144
11.1;6.1. NICOTINAMIDE ADENINE DINUCLEOTIDE;145
11.2;6.2. FLAVINS;149
11.3;6.3. UBIQUINONE;157
11.4;6.4. PLASTOQUINONE;160
11.5;6.5. CYTOCHROME c;164
12;Chapter 7. Photosynthesis;173
12.1;7.1. INTRODUCTION;173
12.2;7.2. BACTERIA;174
12.3;7.3. GREEN PLANTS AND ALGAE;184
12.4;7.4. SUMMARY AND COMMENTS;186
13;Chapter 8. Vision;187
13.1;8.1. CONVERSION OF LIGHT INTO NERVE IMPULSE;187
13.2;8.2. STRUCTURE OF THE VISUAL PIGMENT AND ITS ABSORPTION SPECTRUM;187
13.3;8.3. ACTION OF LIGHT ON THE VISUAL PIGMENT;189
13.4;8.4. DARK REACTIONS;192
13.5;8.5. SUMMARY AND CONCLUSIONS;193
14;Chapter 9. Drugs;194
14.1;9.1. RADIOSENSITIZERS;194
14.2;9.2. FUROCOUMARINS;201
14.3;9.3. PHENOTHIAZINES;213
15;References;218
16;Index;239