Neurobiology of Metaplasticity

Erscheinungsjahr 2026
ISBN: 978-0-443-23742-3
Verlag: Elsevier Science

Buch, Englisch, 330 Seiten, Format (B × H): 152 mm x 229 mm

Neurobiology of Metaplasticity provides in-depth coverage of research on metaplasticity in the nervous system. Coverage includes metaplasticity induction and expression, pathways and receptors, and metaplasticity impact on behavior, learning, and memory. The book explores metaplasticity in different parts of the nervous system, including the hippocampus, human cortex, spinal cord, and visual cortex. Metaplasticity’s impact on disease states is also explored including dementia, aging, stroke, and depression. Finally the book reviews applications of metaplasticity in drug research, artificial intelligence, and machine learning.

Autoren/Hrsg.

Bashir, Shahid

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften: Forschung und Information Forschungsmethodik, Wissenschaftliche Ausstattung
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft

Inhaltsverzeichnis

1. Overview of Metaplasticity
2. Perspectives of Metaplasticity and Synaptic plasticity; The distinction between neuromodulation of plasticity and Metaplasticity
3. Models of Metaplasticity: Hebbian and Homeostatic synaptic plasticity
4. Metaplasticity Induction and Metaplasticity Expression
5. Homosynaptic Metaplasticity & Heterosynaptic Metaplasticity
6. Hippocampal Metaplasticity
7. Metaplasticity of Human Cortex
8. Metaplasticity within Spinal Cord
9. Metaplasticity in Visual cortex
10. Activity-Dependent Metaplasticity
11. Intrinsic excitability-mediated Metaplasticity
12. Experience-dependent induction of Metaplasticity
13. Pathways and Receptors associated with Metaplasticity
14. Metaplasticity and Behavior
15. Metaplasticity in Learning and Memory formation
16. Stress/Depression and Metaplasticity
17. Metaplasticity and diseases, including, but not limited to, AD, Ageing, ASDa, Stroke, etc.
18. Effects of drugs on Metaplasticity
19. Metaplasticity and Non-invasive brain stimulation techniques (NIBS; TMS, tDCS, TBS)
20. Applications of Metaplasticity in Research Techniques and Drug Development
21. Artificial Intelligence and Machine learning in Metaplasticity

Über Autor(innen)

Bashir, Shahid
Dr. Shahid Bashir is currently working as a Neuroscientist at the King Fahad Specialist Hospital - Dammam. He received his PhD from the University of Freiburg. Dr. Bashir's research focus is in establishing cortical plasticity biomarkers using non-invasive transcranial magnetic stimulation (TMS) in combination with electroencephalography (EEG) and electromyography (EMG). Currently his research revolves around enhancing the concepts of synaptic plasticity in normal individuals either with or without pharmacological interventions. The use of such biomarkers holds special promise for better understanding the pathophysiology behind diseases like TBI and aging. He is also interested in combining navigated TMS with brain imaging to explore cross-modal plasticity following brain lesions.