Photopolymerizable Porous Polyorganophosphazenes

Degradable Matrices for Tissue Engineering
2015
ISBN: 978-3-658-09319-8
Verlag: Springer

Buch, Englisch, 75 Seiten, Format (B × H): 148 mm x 210 mm, Gewicht: 1358 g

Reihe: BestMasters

Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes). In order to tailor their biological and chemical properties, she further modified these macromolecules by adding functional moieties via thiol-ene chemistry. The author used the same photochemistry for crosslinking to obtain a mechanically stable network. She further altered the degradation rate of the matrix as well as the mechanical properties by adding blending agents and created a porous matrix, which is necessary for cell invasion and communication, by a newly developed photocrosslinking particulate-leaching method. Thus, a modular hybrid system was established which is able to adapt to different microenvironments based upon tissue type.

Zielgruppe

Research

Autoren/Hrsg.

Aigner, Tamara Bernadette

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Naturwissenschaften Chemie Organische Chemie Biochemie

Inhaltsverzeichnis

Polyphosphazenes as Biocompatible and Biodegradable Polymers.- Functionalization and Crosslinking with Thiol-ene Chemistry.- Matrix Formation Using a Photocrosslinking Particulate-Leaching Technique.- Tailored Physical and Biochemical Properties by Blending.

Über Autor(innen)

Tamara Bernadette Aigner completed her master’s thesis in biological chemistry at Johannes Kepler University in Linz and South Bohemian University in Ceské Budejovice.