Zhou Principles and Applications of Therapeutic Ultrasound in Healthcare

1. Auflage 2015
ISBN: 978-1-4665-1028-9
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 378 Seiten

Therapeutic uses of ultrasound include ablation of kidney stones and tumors and newer applications, such as drug delivery and denervation. Suitable as a textbook or as a quick reference for medical device engineers, research scientists, and healthcare professionals, this text systemically introduces the concepts, principles, construction, and application of therapeutic ultrasound devices. It discusses the fundamental physical principles of biomedical acoustics, ultrasound calibration methods, structures of commercially available therapeutic ultrasound systems, and various applications of ultrasound therapy in clinics.

Zielgruppe

Biomedical engineers and medical device engineers, healthcare professionals, and those taking medical device or medical imaging courses.

Autoren/Hrsg.

Zhou, Yufeng

Fachgebiete

• Naturwissenschaften Physik Physik Allgemein
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Nuklearmedizin, PET, Radiotherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Radiologie, Bildgebende Verfahren
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Medizinische Biotechnologie

Inhaltsverzeichnis

Introduction: ultrasound evolution for healthcare

Principle of biomedical ultrasound

Wave equation

Propagation characteristics

Ultrasound transducer

Acoustic nonlinearity

Bubble cavitation

Acoustic radiation force

Calibration of therapeutic ultrasound instruments

Acoustic pressure waveform and distribution measurement

Acoustic intensity measurement

Cavitation detection

Thermal field evaluation

Ultrasound hyperthermia

Technical realization

Thermometry

Biological aspects

Clinical aspects

Shock wave lithotripsy

Evolution of shock wave lithotripsy

Principle of shock wave generation

Mechanisms of stone fragmentation and renal injury

Technical improvements

Limitations

Shock wave therapy

Review of shock wave therapy

Shock wave treatment of the bone

Shock wave treatment in tendopathies and tendinosis calcerea

Shock wave in wound healing

High-intensity focused ultrasound for tumor ablation

History and principle of HIFU

System construction and treatment procedure

Clinical applications

HIFU-induced artery rupture and immune response

Prospective techniques

Ultrasound-mediated drug delivery / gene therapy

Transdermal drug delivery

Sonoporation for drug delivery and gene therapy

Ocular drug delivery and cataract therapy

Blood-brain barrier disruption

Hemostasis and vessel occlusion

Principle of hemostasis

Vessel occlusion

Sonothrombolysis

Transcranial Doppler ultrasound on ischemic stroke treatment

Ultrasound catheter for thrombolysis

Neurologic application

Ultrasound denervation

Nerve regeneration and simulation

Histotripsy

Interaction of microbubble with HIFU burst

Interaction of boiling bubble with HIFU burst

Clinical applications

Microbubble-based molecular imaging and therapy

Targeted micro- and nano-bubbles

Molecular ultrasound imaging

Targeted therapy by targeted microbubble