Buch, Englisch, 208 Seiten, Format (B × H): 195 mm x 244 mm, Gewicht: 605 g
Advancing Personalized Health Care
Buch, Englisch, 208 Seiten, Format (B × H): 195 mm x 244 mm, Gewicht: 605 g
ISBN: 978-0-12-397336-8
Verlag: Elsevier Science Publishing Co Inc
Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development.
With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development.
Zielgruppe
<p>Pharmaceutical scientists involved in biologics research and drug development, including clinical pharmacologists, toxicologists, pathologists, bioinformaticians and biostatisticians and clinical researchers.</p>
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
Weitere Infos & Material
Preface
Acknowledgements
1. Application of TS in clinical development
2. Personalized Healthcare (PHC) in cancer
3. PHC in autoimmune diseases
4. PHC in respiratory diseases
5. miRNA as potential Diagnostic Marker
6. Toxicogenomics
7. Translating Biomarker Discovery into Companion Diagnostics Through Validation and Regulatory Consideration
