Chemical Biology of Sulfur

Erscheinungsjahr 2020
ISBN: 978-1-83916-144-5
Verlag: RSC Publishing

Buch, Englisch, 430 Seiten, Format (B × H): 165 mm x 241 mm, Gewicht: 793 g

This volume aims to provide an in-depth view of the complete biochemistry of sulfur with an emphasis on aspects not covered elsewhere. Given its role in the formation of proteins and presence in the amino acids methionine and cysteine, sulfur is essential to life. Current literature on the biochemistry of sulfur is vast and widely dispersed, as such this volume is intended as a single-source for everything concerning sulfur biochemistry from metabolic roles of inorganic sulfur, to thiol and thioether chemical biology, to the university of cysteine chemistry in proteomes. Authored by a renowned biochemist and experienced writer and educator, this book is ideal for students and researchers in biochemistry, biology and the life sciences with an interest in sulfur and its role in life.

Autoren/Hrsg.

Walsh, Christopher T

Fachgebiete

• Naturwissenschaften Biowissenschaften Enzymologie
• Naturwissenschaften Chemie Organische Chemie
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

Introduction to Sulfur Chemical Biology;

Sulfate Reducing Bacteria;

Sulfide Oxidizing Bacteria;

Organosulfur Metabolites in Biological Systems;

The Nucleophilic Thiolate in Cysteine and Cysteamine Scaffolds;

Protein Cysteine Persulfides and Fe-S Clusters: Intersection of Organic and Inorganic Sulfur Biochemistry;

Cysteine to Taurine: Thiol to Sulfonic Acid;

Methionine: Thioether Biological Chemistry;

One-electron vs. Two-electron Reaction Manifolds in Sulfur Enzymology;

Sulfuryl Transferases and Sulfatases;

C-S Bond Formations in Primary and Secondary Metabolism;

Cysteinyl Proteomes I: Metal Coordination and Catalytic Intermediates;

The Posttranslational Cysteinyl Proteome;

Cysteinyl Proteomes: Exotic Modifications;

A Traverse Through Sulfur Chemical Biology