Aptamers

1. Auflage 2016
ISBN: 978-981-4669-83-2
Verlag: Pan Stanford

Buch, Englisch, 386 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 688 g

Aptamers, often termed as ‘chemical antibodies,’ are an emerging class of synthetic ligands for efficient target-specific molecular recognition. The objective of this book is to highlight recent advances and potential of aptamers in various disease conditions. This book focuses on the applications of aptamers in targeted nanotherapy, detection, and in molecular imaging in various disease conditions such as cancer, neurological diseases and infectious diseases.

Zielgruppe

Academic and Postgraduate

Autoren/Hrsg.

Veedu, Rakesh N.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Biochemie (med.)
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie

Inhaltsverzeichnis

Aptamers-General Introduction. History of aptamer development. Peptide aptamers: Development and applications. Aptamer selection methodologies. Selection and application of catalytically active oligonucleotides. Aptamer Development for Therapeutic Applications. Stem-cell specific aptamers for targeted cancer therapy. Aptamers as therapeutic tools in neurological diseases. Aptamers in bacterial, viral and parasitic diseases. Aptamers for Targeted Drug Delivery & Nanotherapy. Aptamers as tools for targeted drug delivery. Aptamer-liposome conjugates: Current art and future prospects. Application of Aptamers as Biosensors. Aptamers in medical diagnosis. Aptamers for Target Specific Imaging. Molecular imaging utilizing aptamer-targeted probes. Clinical Utility Scope and Limitations of Aptamers. First therapeutic aptamer: VEGF-targeting Macugen. Aptamers: Scope, limitations and future prospects.

Über Autor(innen)

Rakesh N. Veedu