Biochemistry

An Integrative Approach with Expanded Topics, International Adaptation
1. Auflage 2022
ISBN: 978-1-119-82080-2
Verlag: John Wiley & Sons Inc

Buch, Englisch, 1008 Seiten, Format (B × H): 276 mm x 220 mm, Gewicht: 2226 g

Biochemistry, An Integrative Approach with Expanded Topics, offers a unique approach to the subject, emphasizing problem-solving and critical thinking over rote memorization. It integrates subjects of interest to undergraduates majoring in, biochemistry, life science, and beyond while preserving a chemical perspective. The book covers DNA, RNA, gene regulation, synthetic proteins, omics, plant biochemistry, and more. Key concepts such as metabolism, are introduced and then revisited and cross-referenced throughout the text to establish pattern recognition and help students commit their new knowledge to long-term memory. Emphasis is also laid on problem-solving and reasoning skills essential to life sciences, including data analysis and research assessment. This edition of the book aims to empower students studying a range of disciplines to develop a lasting foundation in biochemistry and metabolism.

Autoren/Hrsg.

Tansey, John T.

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie Biochemie

Inhaltsverzeichnis

1 The Chemical Foundations of Biochemistry 1

2 Nucleic Acids 27

3 Proteins I: An Introduction to Protein Structure, Function and Purification 69

4 Proteins II: Enzymes, Allosterism and Receptor-Ligand Interactions 133

5 Membranes and an Introduction to Signal Transduction 193

6 Carbohydrates I: Mono- and Disaccharides, Glycolysis, Gluconeogenesis, and the Fates of Pyruvate 217

7 The Common Catabolic Pathway 269

8 Carbohydrates II 315

9 Lipids I: Fatty Acids, Steroids, and Eicosanoids; Beta-Oxidation and Fatty Acid Biosynthesis 363

10 Lipids II: Metabolism and Transport of Complex Lipids 415

11 Amino Acid and Amine Metabolism 461

12 Regulation and Integration of Metabolism 505

13 Nucleotide and Deoxynucleotide Metabolism 541

14 DNA Replication, Damage, and Repair 571

15 RNA Synthesis and Processing 611

16 Protein Biosynthesis 643

17 Control and Regulation of Gene Expression 673

18 Determination of Macromolecular Structure 715

19 Protein Production, Folding, and Engineering 745

20 Bioinformatics and Omics 775

21 Signal Transduction 801

22 Protein Trafficking 833

23 Photosynthesis and Nitrogen Fixation 853

TECHNIQUES T-1

SOLUTIONS A-1

GLOSSARY G-1

INDEX I-1

Über Autor(innen)

John T. Tansey received his B.S. in Biochemistry and Molecular Biology from the University of Massachusetts, Amherst, and his PhD in Biochemistry from Wake Forest University. John has been teaching for the past seventeen years in the Chemistry department and Biochemistry and Molecular Biology program at Otterbein University, a primarily undergraduate institution outside Columbus, Ohio. He has also taught at the community college and graduate levels. John was awarded both the Best New Teacher and Master Teacher awards from his university. He is an education fellow of the American Society for Biochemistry and Molecular Biology (ASBMB) and is a member of the editorial board of Biochemistry and Molecular Biology Education (BAMBEd).