Sherman / Watson Ethanol and the Liver

Mechanisms and Management
Erscheinungsjahr 2002
ISBN: 978-1-4200-2427-2
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 718 Seiten

Distilling the available knowledge on ethanol-induced liver damage and directly complementing the available bio-medical literature, Ethanol and the Liver covers pathogenic and clinical aspects of alcoholic liver disease. Providing broader coverage of the subject than any available monograph, the editors and their panel of experts relate basic science to pathogenesis and treatment modalities and explore future developments.

Coverage includes:

- Histopathology-fatty liver, alcoholic hepatitis, and cirrhosis

- Ethanol metabolism and its consequences

- Mechanisms in the pathogenesis of ALD, including genetics, immunology, and insulin-like growth factors

- Extrahepatic effects of ALD and the role of alcohol in potentiating liver damage due to other etiologies

- Interaction of alcohol with viral hepatitis

- Epidemiology, diagnosis, and treatment

- Management strategies, including transplantation

The vast amount of knowledge and expertise gathered in this book make it an unparalleled resource.

Autoren/Hrsg.

Sherman, David

Watson, Ronald Ross

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hepatologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Innere Medizin

Inhaltsverzeichnis

SPECIFIC LESIONS
Alcoholic Fatty Liver, AJ. Bathgate and K.J. Simpson
Alcoholic Hepatitus, H. Denk, K. Zatloukal, and C. Stumptner
Fibrosis in Alcoholic Cirrhosis, S.W. French

DIRECT AND INDIRECT CONSEQUENCES OF ALCOHOL METABOLISM
Genetics of Ethanol Metabolism and Alcoholic Liver Disease, P.Y. Kwo and D.W. Crabb
Acetaldehyde Adducts: Role in Ethanol-Induced Liver Disease, J. Koskinas

MECHANISMS OF DAMAGE
Free Radicals and Alcohol-Induced Liver Injury, E. Albano
Ethanol and the Hepatic Microcirculation, R.S. McCuskey
Cytokines and Alcohol Liver Disease, F.J. Laso, J.I. Madruga, and A. Orfao
Adhesion Molecules and Chemokines in Alcoholic Liver Disease, N.C. Fisher and D.H. Adams
Role of Endotoxin and Kupffer Cells as Triggers of Hypoxia-Reoxygenation in Alcoholic Liver Injury, R.G. Thurman, B.U. Bradford, K.T. Knecht, Y. Iimuro, G.E. Arteel, M. Yin, H.D. Connor, C. Rivera, J.A. Raleigh, M.V. Frankenberg, Y. Adachi, D.T. Forman, D. Brenner, M. Kadiiska, and R.P. Mason
Ethanol and Protein Turnover, E. Volpi
Insulin-Like Growth Factors: Clinical and Experimental, A.J. Donaghy
Cellular Mechanisms of Liver Regeneration and the Effect of Alcohol, M. Phillips, E. Kashef, and R. Hughes
Alcohol and Hepatocellular Carcinoma, S.D. Ryder
Animal Models of Ethanol-Induced Liver Disease H.A. Järveläinen and K.O. Lindros

EPIDEMIOLOGY AND DIAGNOSIS
Epidemiology and Comparative Incidence of Alcohol-Induced Liver Disease, J.B. Saunders and B.M. Devereaux
Serum Diagnosis of Alcoholic Liver Disease and Markers of Ethanol Intake, O. Niemelä

EXTRAHEPATIC EFFECTS
Extrahepatic Effects of Alcohol: An Overview, H.L. Reeves and C.P. Day
Endocrine System, C. Gluud
Cardiomyopathy and Skeletal Muscle Myopathy, A. Urbano-Márquez, J. Fernández-Solà, and R. Estruch
Cerebral Consequences of Alcoholic Liver Disease, R.F. Butterworth

MANAGEMENT
General Management of Alcoholic Liver Disease, M. Phillips and J. O'Grady
The Role of the Psychiatrist in the Treatment of Alcoholic Liver Disease, J. Martínez-Raga and E.J. Marshall
Pharmacological Treatment for Alcoholic Hepatitis and Cirrhosis: Present Practice and Future Strategies, P. Mathurin and T. Poynard
Nutritional Support in Alcoholic Liver Disease: Practical Management and Future Strategies, A. Madden
Alcohol and Viral Hepatitis: Interactions and Management, A. Parés and J. Caballería
Liver Transplantation in Alcoholic Liver Disease, S.P. Pereira and R. Williams