Buch, Englisch, 209 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 547 g
ISBN: 978-981-97-0390-6
Verlag: Springer Nature Singapore
This book provides the reader with the latest research on vibrational circular dichroism (VCD) spectroscopy including its useful features and applications to many fields. The book starts from an unresolved question in gel chemistry of how component molecules are organized in the flexible fibrils of gels. VCD spectroscopy was successful in giving a clear answer to this mystery. The book also describes a key aspect of this technique lay in the fact that VCD signals were remarkably enhanced when chiral molecules formed a stereoregular molecular array over a few hundred nanometers. VCD spectroscopy was also applied to other topics involving chiral molecules such as the chiral discrimination mechanism in heterogeneous asymmetric catalysis and the build-up of supramolecular chirality in molecular crystals. Furthermore, the book covers the recent instrument developments leading to multi-dimensional VCD measurements with the coordinates of wavenumber, space and time. This progress has opened up new biological and medical applications such as the heterogenous distributions of protein domains in insect wings and the quality control of chiral drugs. The last part of the book presents the possibility of medical diagnosis of Alzheimer’s disease through multi-dimensional VCD analyses.
This book appeals not only to researchers and students who study spectroscopy but also to ones in catalysis, biology and medicine as users of the VCD methods.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Chemie Analytische Chemie Magnetresonanz
- Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Public Health, Gesundheitsmanagement, Gesundheitsökonomie, Gesundheitspolitik
- Naturwissenschaften Chemie Organische Chemie
- Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde
- Naturwissenschaften Chemie Anorganische Chemie
Weitere Infos & Material
Preface.- Chapter 1. Introduction.- Chapter 2. Basic features of vibrational circular dichroism (VCD) spectroscopy: A unique role for analyzing supramolecular chirality.- Chapter 3. Construction of the multi-dimensional VCD system.- Chapter 4. Molecular organization of gel fibrils as revealed by VCD.- Chapter 5. Dynamical VCD for sol-gel transformation.- Chapter 6. VCD enhancement on coordination: Mono-nuclear metal complexes.- Chapter 7. Chiral tectonics promoted by VCD: Multi-nuclear complexes.- Chapter 8. Solid-state VCD of inorganic intercalation compounds.- Chapter 9. VCD probing intermolecular interactions: Molecular crystals, acid-base pairs, host-guest association and solvation.-Chapter 10. VCD challenged to interfacial supramolecular chirality.- Chapter 11. VCD of inorganic supramolecular chirality.- Chapter 12. Use of circularly polarized infra-red light to liquid crystals.- Chapter 13. VCD of biological substances: Effects of D-amino acid residues on supramolecular chirality.- Chapter 14. Microscopic VCD scanning of biological organs.- Chapter 15. Future perspectives of VCD.- Bibliography: 17 year’s running on a tightrope.