Saks Molecular System Bioenergetics

Energy for Life
1. Auflage 2008
ISBN: 978-3-527-62110-1
Verlag: Wiley-VCH
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 605 Seiten, E-Book

In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.

Autoren/Hrsg.

Saks, Valdur

Inhaltsverzeichnis

Introduction

MOLECULAR SYSTEM BIOENERGETICS: BASIC PRINCIPLES, ORGANISATION AND DYNAMICS OF CELLULAR ENERGETICS

Cellular Energy Metabolism and Integrated Oxidative Phosphorylation

Organization and Regulation of Mitochondrial Oxidative Phosphorylation

Integrated and Organized Cellular Energetic Systems: Theories of Cell Energetics, Compartmentation and Metabolic Channeling

On the Network Properties of Mitochondria

Structural Organization and Dynamics of Mitochondria in the Cells In Vivo

ENERGY TRANSFER NETWORKS, METABOLIC FEEDBACK REGULATION AND MODELING OF CELLULAR ENERGETICS

Mitochondrial VDAC and its Complexes

Phospho-Creatine Circuit:

Integration of Adenylate Kinase, Glycolytic and Glycogenolytic Circuits in Cellular Energetics

Signaling by AMP-Activated Protein Kinase

Developmental and Functional Consequences of Disturbed Energetic Communication in Brain of Creatine Kinase Deficient Mice

System Analysis of Cardiac Energetics - Excitation-Contraction Coupling

Principles of Mathematical Modeling and In Silico Studies of Integrated Systems of Cellular Energetics

Modeling Energetics of Ion Transport, Membrane Sensing and System Biology of the Heart

APPLIED MOLECULAR SYSTEM BIOENERGETICS

Mitochondrial Adaptation to Exercise and Training - A Physiological Approach

Mitochondrial Medicine: The Central Role of Cellular Energetic Depression and Mitochondria in Cell Pathophysiology

Tumour Cell Energetic Metabolome

AMPK and the Metabolic Syndrome

A Systems Biology Perspective of Obesity and Type 2 Diabetes

Über Autor(innen)

Valdur Saks is Professor of Bioenergetics and Biochemistry at the University of Grenoble, France, and Head of the Laboratory of Bioenergetics at the National Institute of Chemical and Biological Physics in Tallinn, Estonia. A graduate of Moscow University, he was the long-time head of the Laboratory of Cardiac Bioenergetics in Moscow, Russia, before taking up his present positions. Professor Saks has authored over 220 scientific publications and has received numerous scientific awards, including the USSR State Prize in Science and the Internatinoal "Research and Development" Award sponsored by the U.N. and UNICEF. He is a member of the International Society for Heart Research and of the American Physiological and Biophysical Societies.