Manual of Blood Platelets

Morphology, Physiology and Pharmacology
Erscheinungsjahr 2020
ISBN: 978-93-5270-202-2
Verlag: JAYPEE BROTHERS MEDICAL PUBLISHERS P LTD

Buch, Englisch, 281 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 905 g

Platelets are tiny blood cells that help the body form clots to stop bleeding. Antiplatelet medications, such as aspirin and clopidogrel, are commonly used to thin the blood which limits clotting and reduces the risk of heart attack.

This book is a comprehensive guide to blood platelets for haematologists.

Beginning with discussion on platelet structure, morphology, function and physiology, the next chapters cover the role of calcium in platelet activation and calcium modulation by cyclic nucleotides.

The following sections explain the pharmacology of antiplatelet drugs, antiplatelet therapies, aspirin resistance, and the association of diabetes mellitus with major platelet dysfunction.

The book concludes with chapters on acute coronary problems, interaction between endothelial cells and platelets, and blood biocompatibility studies.

Authored by a Minneapolis-based expert in the field, the text is further enhanced by clinical photographs, diagrams and tables.

Key points

- Comprehensive guide to blood platelets for haematologists

- Extensive coverage of antiplatelet drugs and resistance

- Recognised author from University of Minnesota

- Highly illustrated with clinical photographs, diagrams and tables

Autoren/Hrsg.

Rao, Gundu Hr

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hämatologie, Transfusionsmedizin

Inhaltsverzeichnis

Introduction

- Platelet Ultrastructure Morphology

- Platelet Morphology and Function

- Platelet Morphology and Dysfunction

- Platelet Physiology

- Platelet Activation Mechanisms

- Role of Calcium in Platelet Activation

- Eicosanoid Metabolism and Platelet Function

- Calcium Modulation by Cyclic Nucleotides

- Pharmacology of Antiplatelet Drugs

- Antiplatelet Therapies

- Aspirin Resistance

- Platelet Dysfunctions Associated with Diabetes Mellitus

- Platelet Hyperfunction as a Risk Promoter for Acute Coronary Events

- Epinephrine-induced Platelet Membrane Modulation

- Platelet-Vessel Wall Interactions

- Blood Biocompatibility Studies

 

Afterword

Bibliography

Index

Über Autor(innen)

Gundu HR Rao PhD

Emeritus Professor, Laboratory Medicine and Pathology, Director, Thrombosis Research, Lillehei Heart Institute, Academic Health Centre, University of Minnesota, Minneapolis, USA