Treatment of Multiple Myeloma and Related Disorders

Erscheinungsjahr 2008
ISBN: 978-0-521-51503-0
Verlag: Cambridge University Press

Buch, Englisch, 214 Seiten, Format (B × H): 208 mm x 260 mm, Gewicht: 696 g

Due to major advances in understanding the biology and pathogenesis of the disease, the management of multiple myeloma is changing rapidly. New diagnostic and prognostic criteria have been introduced, and treatment options are multiplying with high-dose chemotherapy regimens, stem cell transplants, and the development of novel agents and immune-based strategies that target tumor cells directly. This book is aimed at the practitioner who is looking to put these advances into clinical context. It will serve as an up-to-date resource for treatment of myeloma and related disorders. Chapters are written by international authorities and contain color photos, diagrams, and algorithms outlining preferred treatment strategies. Relevant scientific information is integrated throughout, but the focus here is on providing practical therapeutic guidance for oncologists and hematologists caring for myeloma patients. The book covers all myeloma subtypes and related disorders, including amyloidosis, Waldenstrom macroglobulinemia, plasmacytoma, MGUS, and POEMS syndrome.

Autoren/Hrsg.

Rajkumar, S. Vincent

Kyle, Robert A.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hämatologie, Transfusionsmedizin

Inhaltsverzeichnis

1. Diagnosis and genetic classification of MM Rafael Fonseca and P. Leif Bergsagel; 2. Staging and risk-stratification of MM Keith Stewart; 3. Treatment of newly diagnosed MM S. Vincent Rajkumar and Robert A. Kyle; 4. Maintenance therapy in MM Sagar Lonial and Jonathan L. Kaufman; 5. Treatment of relapsed and relapsed/refractory MM Marc S. Raab, Paul G. Richardson and Kenneth C. Anderson; 6. Diagnosis and treatment of myeloma bone disease G. David Roodman; 7. Treatment of myeloma related complications Joan Bladé and Laura Rosiñol; 8. Autologous transplantation for MM J.-L. Harousseau; 9. Allogeneic stem cell transplantation for MM William I. Bensinger; 10. Immunoglobulin light chain amyloidosis (AL) Morie A. Gertz and Suzanne R. Hayman; 11. Waldenstrom's macrogloblinemia/lymphoplasmacytic lymphoma Steven P. Treon and Giampaolo Merlini; 12. Diagnosis, risk-stratification and management of solitary plasmacytoma Meletios A. Dimopoulos and Efstathios Kastritis; 13. Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma Robert A. Kyle and S. Vincent Rajkumar; 14. Diagnosis and treatment of POEMS syndrome Angela Dispenzieri.

Über Autor(innen)

Rajkumar, S. Vincent
Dr. S. Vincent Rajkumar is Professor of Medicine at Mayo Clinic College of Medicine and Chair of the Mayo Clinic Myeloma, Amyloidosis, and Dysproteinemia Group. He has authored more than 250 papers and book chapters, primarily in the field of myeloma and related plasma cell disorders. He has led several clinical trials investigating the role of new agents in myeloma. Dr Rajkumar is a member of the American Society of Clinical Oncology Cancer Education Committee as well as the Scientific Advisory Board of the International Myeloma Foundation. Dr. Rajkumar is an associate editor of the Mayo Clinic Proceedings and is on the editorial boards of American Journal of Oncology Review and Leukemia Research.

Kyle, Robert A.
Dr Robert A. Kyle is Professor of Medicine and Laboratory Medicine at Mayo Clinic in Rochester, Minnesota. He served as the William H. Donner Professor of Medicine and Laboratory Medicine and was Section Head and Chairman of the Division of Hematology. Dr. Kyle is one of the most respected authorities in the field of multiple myeloma and related disorders and has authored more than 750 papers and book chapters, primarily in the field of myeloma and related plasma cell disorders. He has led several major clinical trials and epidemiologic studies in the field. Dr Kyle is currently Chairman of the Scientific Advisory Board of the International Myeloma Foundation, Chairman of the Scientific Advisory Committee of the International Waldenström's Macroglobulinemia Foundation, and President of the International Society of Amyloidosis. During his career, Dr. Kyle has been recognized as the first recipient of the Robert A. Kyle Award for the Waldenstrom's Macroglobulinemia Foundation, first recipient of the Robert A. Kyle Lifetime Achievement Award from the International Myeloma Foundation, Mayo Clinic's Henry S. Plummer Distinguished Internist Award, Mayo Clinic's Distinguished Clinician Award, and the Mayo Clinic's Distinguished Alumni Award. He was also recipient of the 2007 David Karnofsky Award and Lecture at ASCO.