Advances in Gastrointestinal Cancer Therapy

Spotlight on Nanoarchitectures
Erscheinungsjahr 2025
ISBN: 978-0-443-21582-7
Verlag: Elsevier Science

Buch, Englisch, 330 Seiten, Format (B × H): 191 mm x 235 mm

Advances in gastrointestinal cancer therapy: Spotlight on nanoarchitectures considers applications of nanostructures in treatment of gastrointestinal tumors and their capacity in improving efficacy of therapeutics, The book has a strong focus on overcoming challenges in gastrointestinal cancer therapies such as drug resistance, introduction of nanomedicine for drug and gene delivery, and new insight for clinical trials in treatment of patients with gastrointestinal tumors. In 25 chapters Advances in gastrointestinal cancer therapy: Spotlight on nanoarchitectures describes the multiple problems in treatment of gastrointestinal cancers including drug resistance, radio-resistance, inability to reaching to tumor site, degradation of genetic tools by RNase enzymes, and acidic pH of tumor microenvironment that may negatively affect efficacy of chemotherapeutic agents by making changes in their structure. This book is a valuable resource for Students, researchers and academicians in oncology and medical engineering.

Autoren/Hrsg.

Rabiee, Navid

Ashrafizadeh, Milad

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

Section I: Nanomedicine and cancer 1. Cancer therapy challenges 2. Development of therapy resistance in cancer 3. An overview of oncogenic and onco-suppressor pathways in cancer 4. Role of nanomedicine in cancer therapy: Promising and opportunities 5. Optimization, design and development of nanostructures for purpose of cancer therapy: Principles of cargo loading and exploring new emerging platforms Section II: Gastrointestinal tumors: Pathogenesis and progression 6. Gastric cancer: Epidemiology, pathogenesis and progression factors 7: Liver cancer: Epidemiology, pathogenesis and progression factors 8. Colorectal cancer: Epidemiology, pathogenesis and progression factors 9. Pancreatic cancer: Epidemiology, pathogenesis and progression factors 10. Esophageal cancer: Epidemiology, pathogenesis and progression factors Section III: Nanomedicine and gastric cancer 11. Polymeric nanoparticles in gastric cancer therapy 12. Lipid-based nanoparticles in gastric cancer therapy 13. Carbon-based nanoparticles in gastric cancer therapy 14. Metal-based nanoparticles in gastric cancer therapy Section IV: Nanomedicine and liver cancer 15. Polymeric nanoparticles in liver cancer therapy 16. Lipid-based nanoparticles in liver cancer therapy 17. Carbon-based nanoparticles in liver cancer therapy 18. Metal-based nanoparticles in liver cancer therapy Section V: Nanomedicine and Colorectal cancer Chapter 18: Polymeric nanoparticles in gastric cancer therapy 19. Lipid-based nanoparticles in gastric cancer therapy 20. Carbon-based nanoparticles in gastric cancer therapy Chapter 21: Metal-based nanoparticles in gastric cancer therapy Section VI: Nanomedicine and pancreatic cancer 21. Polymeric nanoparticles in gastric cancer therapy 22. Lipid-based nanoparticles in gastric cancer therapy 23. Carbon-based nanoparticles in gastric cancer therapy 24. Metal-based nanoparticles in gastric cancer therapy Chapter VII: Nanomedicine and esophageal cancer 25. An overview of nanostructures in esophageal cancer therapy

Über Autor(innen)

Rabiee, Navid
Navid Rabiee, Ph.D., is a Postdoctoral research associate at the Sharif University of Technology, Tehran, Iran, and an Invited Visiting Scholar at Macquarie University, Sydney, New South Wales, Australia. Since 2016, he is working on several fields with a multidisciplinary approach by blending modern molecular and cellular biology/biochemical sciences with engineering principles to design the next generation of medical systems and devices for patient treatment. He is a pioneer in the field of BioInorganic Chemistry with an emphasis on CRISPR delivery with the assistance of inorganic nano-vectors. His work has resulted in the publication of over 200 peer-reviewed journal articles in prestigious journals, including?Nature,?Nature Medicine,?The Lancet,?Nano Today, Biomaterials, Advanced Functional Materials?and etc., 6 books, over 20 chapters and 5 conference papers

Ashrafizadeh, Milad
Dr Milad Ashrafizadeh is a researcher in Sabanci university, Turkey and obtained his degree in field of Veterinary Medicine in 2020. He is an invited scholar in University of Electronic Science & Technology of China. Currently, Milad is an Editorial Board in journal of nanostructure in chemistry (IF= 6.39) and is a review editor in Frontiers journals. He has published review and research articles in international and famous journals in world. Milad has also 4 book chapters. He has published articles in high quality journals including Nanotoday, Coordination Chemistry Reviews, Advanced Science, Carbohydrate Polymers, Journal of Controlled Release and Advances in Colloid and Interface Science, among others. His interests include nanomedicine, application of nanoparticles for drug and gene delivery, targeted cancer therapy, non-coding RNAs in cancer and development of biosensors.