Hirschsprung's Disease and Allied Disorders

Fourth Auflage 2019
ISBN: 978-3-030-15646-6
Verlag: Springer

Buch, Englisch, 462 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 1208 g

This is the third edition of a comprehensive study of the neuronal disorders of the lower gastrointestinal tract in children. Important new studies and progress in research on bowel motility and motility disorders are covered in detail as well as new aspects concerning the embryology, functional anatomy of the enteric nervous system. In particular new insights have been received from the studies in the genetics of Hirschsprung's disease. Special emphasis is laid on new surgical techniques, especially on the laparoscopic approach in combination with Soave's or Duhamel's technique.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Puri, Prem

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Pädiatrische Chirurgie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Gastrointestinale & Colorectale Chirurgie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Gastroentereologie, Proktologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Pädiatrie, Neonatologie

Inhaltsverzeichnis

Hirschsprung’s Disease: A Historical Perspective.- Development of the Enteric Nervous system.- Functional Anatomy of the Enteric System.- Normal Colonic Morphology and Motor Function.- Animal Models of Hirschsprung’s Disease.- Familial Hirschsprung’s Disease.- Genetics of Hirschsprung’s Disease.- Stem cell Therapy for Enteric neuropathies.- Pathophysiology of Hirschsprung’s Disease.- Epidemiology and Clinical Characteristics of Hirschsprung’s Disease.- Associated Anomalies and Syndromes in Hirschsprung’s Disease.- Association between Hirschsprung’s Disease and Multiple Endocrine Neoplasia Type 2a.- Hirschsprung’s Associated Enterocolitis.- Radiological Diagnosis of Hirschsprung’s Disease.- Manometeric Diagnosis of Hirschsprung’s Disease.- Rectal Biopsy for the diagnosis of Hirschsprung’s Disease.- Histopathological Diagnosis of Hirschsprung’s Disease.- Total Colonic Aganglionosis.- Hirschsprung’s Disease in adolescents and adults.- Variants of Hirschsprung’s Disease.- Megacystis-Microcolon-Intestinal Hypoperistalsis syndrome.- Degenerative Hollow Visceral Myopathy Mimicking Hirschsprung’s Disease.- Transanal Pull-Through operation for rectosigmoid Hirschsprung’s Disease.- Laparoscopically Assisted Pull-Through operation for Hirschsprung’s Disease.- Redo Surgery for Hirschsprung’s Disease.- Early and late Complications following Pull-Through operation for Hirschsprung’s Disease.-Morphological Basis of Persistent bowel problems following a properly performed pull-through operation for Hirschsprung’s Disease.- Bowel Management for the treatment of Chronic constipation and soiling in patients operated for Hirschsprung’s Disease.- Inflammatory Bowel Disease in patients with Hirschsprung’s Disease.- Intestinal Transplantation for Total Intestinal Aganglionosis.- Urological and Sexual outcome in patients with Hirschsprung’s Disease.- Longterm Outcome and Quality of life after treatment of Hirschsprung’s Disease.

Über Autor(innen)

Professor Prem Puri ,MBBS, LRCP, LRCS(Ed), DCH, MS, FRCS, FRCS(Ed),FACS, FC Paed Surg(SA)(Hon), FAAP(Hon), D.Sc(Hon)  is the Newman Clinical Research Professor at the University College Dublin School of Medicine and Medical Science and Consultant Paediatric Surgeon at the Beacon Hospital.  He is currently the President of the World Federation of Associations of Paediatric Surgeons (WOFAPS) FOUNDATION and Secretary of the International Board of Pediatric Surgical Research.  He is Past President of the World Federation of Associations of Pediatric Surgeons (WOFAPS), and Past President of the European Paediatric Surgeons Association (EUPSA).  He is Editor-in-Chief of Paediatric Surgery International, and also on the Editorial Board of several other journals.  He was the Director of Research at the National Children’s Research Centre (NCRC), Dublin, Ireland from 1989–2009 and President of the NCRC from 2009–2016.

He has been awarded many Honorary Fellowships, including the American Surgical Association (ASA), American Academy of Paediatrics, American Paediatric Surgical Association, Canadian Association of Pediatric Surgeons, Japanese Society of Pediatric Surgeons, and also Argentinean, Austrian, Canadian, Czech, Croatian, Cuban, Indian, South African and Ukrainian paediatric surgical associations.

Professor Puri is known internationally for his research into underlying mechanisms causing birth defects, and innovative treatments, which have benefited children all over the world. He is a multi award-winning researcher whose previous awards include People of the Year Award (Highest Irish National Award), the prestigious Denis Browne Gold Medal by the British Association of Paediatric Surgeons and Rehbein Medal by the European Paediatric Surgeons Association for outstanding contribution to paediatric surgery. He has been a visiting professor to many leading universities all over the world, and invited speaker at over 250 international scientific meetings. He has published 10 books, 147 chapters in textbooks and over 700 articles in peer-reviewed journals.  He is the Editor of Newborn Surgery regarded as the authoritative book in the field, and the 4th edition is now published, and also of the widely acclaimed Pediatric Surgery (Atlas Series) which is in its 2nd edition. His research has been cited over 20,000 times in peer-reviewed articles.