Overview
- Outlines the unique challenges of HSCT and profiles supportive care guidelines for patients with SCD
- Reviews several landmark phase III trials that utilize matched unrelated and haploidentical donors for HSCT in SCD patients
- Written by experts in the field
- Includes supplementary material: sn.pub/extras
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About this book
This book provides a comprehensive, state-of-the art review of hematopoietic stem cell transplantation (HSCT) for sickle cell disease (SCD). The book reviews new data about risk prediction for severe SCD, outlines the unique challenges of HSCT for patients with SCD, profiles the supportive care guidelines for patients who are undergoing HSCT, highlights our current understanding of the best transfusion support for SCD patients prior to, during and after HSCT, and provides new perspectives about the ethics of HSCT for pediatric patients with SCD. Published in the last few years, several landmark phase III trials that utilize matched unrelated and haploidentical donors for HSCT in SCD patients are also placed in context with respect to current management.
Written by experts in the field, Sickle Cell Disease and Hematopoietic Stem Cell Transplantation is a valuable resource for physicians and researchers dealing with and interested in this challenging, yet exciting, curative therapy for sickle cell disease, that will help guide patient management and stimulate investigative efforts.
Written by experts in the field, Sickle Cell Disease and Hematopoietic Stem Cell Transplantation is a valuable resource for physicians and researchers dealing with and interested in this challenging, yet exciting, curative therapy for sickle cell disease, that will help guide patient management and stimulate investigative efforts.
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Keywords
Table of contents (15 chapters)
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Front Matter
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Sickle Cell Disease
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Front Matter
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Hematopoietic Stem Cell Transplantation
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Front Matter
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Back Matter
Reviews
“An authoritative work on hematopoietic stem cell transplantation (HSCT) … . Written by leading expert clinicians and researchers … . this is a very valuable resource for clinicians and scientists dealing with this devastating disease and pursuing a curative therapy.” (Ravi Salgia, Doody's Book Reviews, August, 2018)
Editors and Affiliations
About the editors
Emily Riehm Meier, MD, MSHS
Pediatric Hematologist and Director, Sickle Cell Research, Indiana Hemophilia and Thrombosis Center, Indianapolis, IN, USA
Allistair Abraham, MD
Children’s National Medical Center, Division of Blood and Marrow Transplantation, Washington, DC, USA
Ross M. Fasano, MD
Emory University School of Medicine, Department of Pathology & Laboratory Medicine, Atlanta GA, USA
Pediatric Hematologist and Director, Sickle Cell Research, Indiana Hemophilia and Thrombosis Center, Indianapolis, IN, USA
Allistair Abraham, MD
Children’s National Medical Center, Division of Blood and Marrow Transplantation, Washington, DC, USA
Ross M. Fasano, MD
Emory University School of Medicine, Department of Pathology & Laboratory Medicine, Atlanta GA, USA
Bibliographic Information
Book Title: Sickle Cell Disease and Hematopoietic Stem Cell Transplantation
Editors: Emily Riehm Meier, Allistair Abraham, Ross M. Fasano
DOI: https://doi.org/10.1007/978-3-319-62328-3
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing AG 2018
Hardcover ISBN: 978-3-319-62327-6Published: 05 October 2017
Softcover ISBN: 978-3-319-87292-6Published: 18 August 2018
eBook ISBN: 978-3-319-62328-3Published: 19 September 2017
Edition Number: 1
Number of Pages: XIII, 334
Number of Illustrations: 5 b/w illustrations, 16 illustrations in colour
Topics: Hematology