Overview
- Presents state-of-the-art of research on antimicrobial peptides in human medicine
- Elucidates the immunomodulatory aspects of AMP
- Discusses the potential therapeutic use of AMP
Part of the book series: Birkhäuser Advances in Infectious Diseases (BAID)
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About this book
This book focuses on the importance of human antimicrobial peptides (AMP) in keeping the host healthy and preventing infectious diseases. The first chapters deal with several examples of the role of AMP in different epithelial organs (skin and wound healing, eye, lung, genito-urinary tract, gut), which are exposed to different kinds of infectious microorganisms and as a result produce different patterns of AMP. Examples of the dysregulation of AMP expression and function promoting infections are discussed. The capacity of AMP to restrict the availability of essential metals to bacteria as an efficient antibacterial strategy in nutritional immunity is discussed in the next chapter. Our current understanding of how vitamin D, the sunshine vitamin, influences AMP-expression and how this can affect our health is also addressed. Last but not least, the role of AMP in HIV infection and the immunomodulatory properties of AMP highlight the diverse facets of AMP in host immunity. AMP’s specific functions, including in fighting multi-resistant bacteria, suggest that they may offer therapeutic benefits – a question that is discussed in the final chapter.
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Keywords
Table of contents (10 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
Bibliographic Information
Book Title: Antimicrobial Peptides
Book Subtitle: Role in Human Health and Disease
Editors: Jürgen Harder, Jens-M. Schröder
Series Title: Birkhäuser Advances in Infectious Diseases
DOI: https://doi.org/10.1007/978-3-319-24199-9
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2016
Hardcover ISBN: 978-3-319-24197-5Published: 08 January 2016
Softcover ISBN: 978-3-319-79588-1Published: 30 March 2018
eBook ISBN: 978-3-319-24199-9Published: 24 December 2015
Series ISSN: 2504-3811
Series E-ISSN: 2504-3838
Edition Number: 1
Number of Pages: VI, 158
Number of Illustrations: 10 illustrations in colour
Topics: Immunology, Microbiology