Patel / Kurzrock Early Phase Cancer Immunotherapy

1. Auflage 2018
ISBN: 978-3-319-63757-0
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 331 Seiten, eBook

Reihe: Current Cancer Research

This volume, a state-of-the-art review of early phase clinical trials for cancer immunotherapy, discusses biomarker selection, combinatorial strategies and their safety or toxicity, determination of Phase 2 dosing, endpoints in the setting of radiographic pseudoprogression, histology selection, and novel immunotherapeutics as they relate to early phase cancer immunotherapy.

Zielgruppe

Research

Autoren/Hrsg.

Patel, Sandip Pravin

Kurzrock, Razelle

Inhaltsverzeichnis

Chapter 1 Primer on Cancer Immunotherapy and the Targeting of Native Proteins.- Chapter 2 Pharmacokinetics and Pharmacodynamics of Immunotherapy.- Chapter 3 Immunotherapeutic Biomarkers and Selection Strategies.- Chapter 4 Radiographic Evaluation of Immunotherapy.- Chapter 5 Cellular Therapy.- Chapter 6 Combinatorial Checkpoint Blockade Immunotherapy and Radiation.- Chapter 7 Early Phase Cancer Immunotherapy.- Chapter 8 Immune Checkpoint Combinations with Inflammatory Pathway Modulators.- Chapter 9 Combinations of Genomically and Immune-Targeted Therapies in Early-Phase Clinical Trials.- Chapter 10 Thoracic Immunotherapy.

Über Autor(innen)

Razelle Kurzrock, MD, is Senior Deputy Director for Clinical Science, Chief, Division of Hematology & Oncology, Murray Professor of Medicine, Director, Center for Personalized Cancer Therapy & Clinical Trials Office, University of California, San Diego.Sandip Patel, MD, is Assistant Professor, Cancer Immunotherapy Program, Experimental Therapeutics (Phase 1 Program), Thoracic Oncology, Division of Hematology & Oncology and Center for Personalized Cancer Therapy, UC San Diego Moores Cancer Center.