Paoletti / Kritchevsky Advances in Lipid Research

1. Auflage 2014
ISBN: 978-1-4832-2445-9
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band Volume 6, 438 Seiten, Web PDF

Reihe: Advances in Lipid Research

Advances in Lipid Research, Volume 6 provides information pertinent to brain cholesterol and myelin lipids. This book reviews the various aspects of the physiology, chemistry, and biochemistry of lipids. Organized into seven chapters, this volume begins with an overview of the separation of lipoproteins and discusses lipid metabolism in microorganisms. This text then provides a discussion of lipid metabolism in mycoplasmas. Other chapters consider the various aspects of metabolism of the lipid quinones and explore the relationship between lipids and atherosclerosis as a continuing source of biochemical, medical, and nutritional interest. This book discusses as well a comparative aspect of the development of atherosclerosis and explains the chemistry of bile acids. The final chapter deals with the aspects of steroid separations as well as with regard to separation of other metabolites that may influence lipid metabolism. This book is a valuable resource for biologists, biochemists, scientists, and research workers.

Autoren/Hrsg.

Paoletti, Rodolfo

Kritchevsky, David

Inhaltsverzeichnis

1;Front Cover;1
2;Advances in Lipid Research;4
3;Copyright Page;5
4;Table of Contents;10
5;LIST OF CONTRIBUTORS;6
6;PREFACE;8
7;CONTENTS OF PREVIOUS VOLUMES;14
8;Chapter 1. Practical Methods for Plasma Lipoprotein Analysis;18
8.1;I. Introduction;19
8.2;II. The Physicochemical Basis of Lipoprotein Fractionation;25
8.3;III. Methods Used in Lipoprotein Separations;32
8.4;IV. Practical Methods for Lipoprotein Analysis;46
8.5;V. Conclusions;79
8.6;References;80
9;Chapter 2. The Lipids of Mycoplasma;86
9.1;I. Introduction;86
9.2;II. Lipid Composition and Cellular Location;87
9.3;III. The Nature of Mycoplasmal Lipids;88
9.4;IV. Lipid Nutrition of Mycoplasma;95
9.5;V. Biosynthesis of Lipids by Mycoplasma;102
9.6;VI. Metabolism of Lipids by Mycoplasma;105
9.7;VII. Functional Roles of Lipids in Mycoplasma;111
9.8;Note Added in Proof;119
9.9;References;120
10;Chapter 3. Lipid Quinones;124
10.1;I. Introduction;125
10.2;II. General Considerations;125
10.3;III. Physical and Chemical Properties;131
10.4;IV. Procedures of Isolation;136
10.5;V. Quantitative Analysis;139
10.6;VI. Natural Occurrence and Distribution;140
10.7;VII. Synthesis and Biosynthesis;151
10.8;VIII. Relationship to Nutrition;162
10.9;IX. Metabolic Role of Lipid Quinones;174
10.10;References;187
11;Chapter 4. Comparative Pathogenetic Patterns in Atherosclerosis;198
11.1;I. Introduction;198
11.2;II. Lipoprotein Accumulation in and Injury to Medial Smooth Muscle Cells;200
11.3;III. The Smooth Muscle Cell of the Artery Wall Responds by Proliferating, Migrating, and Modifying Its Metabolism;202
11.4;IV. Smooth Muscle Cell Migration and Colonization into or on Arterial Transplants or Prostheses;204
11.5;V. The Arterial Smooth Muscle Cell Produces Variable Quantities of Collagen, Elastin,
Smooth Muscle Fibers, Ground Substance, and Basement Membrane;207
11.6;VI. Circulating Lipid-Filled Monocyte versus Lipoprotein Filtration in Atherogenesis;211
11.7;VII. The Role of Arterial Lipid Synthesis in the Development of Atherosclerosis in Certain Species;215
11.8;References;219
12;Chapter 5. Chemistry and Metabolism of Bile Alcohols and Higher Bile Acids;224
12.1;I. Introduction;225
12.2;II. Separation and Analysis of Bile Alcohols and Higher Bile Acids;226
12.3;III. Chemistry of Bile Alcohols and Higher Bile Acids;231
12.4;IV. Biosynthesis and Metabolism of Bile Alcohols and Higher Bile Acids;254
12.5;V. Conclusion;266
12.6;References;267
13;Chapter 6. Hydroxy Fatty Acid Metabolism in Brain;272
13.1;I. Background Information;272
13.2;II. Biosynthesis of the 2-Hydroxy Acids;273
13.3;III. Metabolism of 2-Hydroxy Acids;279
13.4;IV. Prostaglandins;285
13.5;V. Hydroxy Fatty Acids in Disease;286
13.6;References;288
14;Chapter 7. Gas Phase Analytical Methods for the Study of Steroids;290
14.1;I. Introduction;291
14.2;II. The Practice of Gas Chromatography;292
14.3;III. Structure-Retention Time Relationships;310
14.4;IV. Separation Methods for Steroid Classes;333
14.5;V. Identification of Steroids by Mass Spectrometry;358
14.6;VI. Quantification;383
14.7;References;401
15;AUTHOR INDEX;410
16;SUBJECT INDEX;430