Flow Cytometry of Hematological Malignacies

2. Auflage 2021
ISBN: 978-1-119-61125-7
Verlag: Wiley

Buch, Englisch, 464 Seiten, Format (B × H): 216 mm x 280 mm, Gewicht: 1162 g

Flow Cytometry of Hematological Malignancies bietet eine Vielzahl grafisch aufbereiteter Ergebnisse, die mit der Durchflusszytometrie bei der Untersuchung der häufigsten Erkrankungen gewonnen wurden. Auch weniger bekannte Krankheiten werden vorgestellt.

Das Fachbuch wurde als Referenzwerk zum schnellen Nachschlagen konzipiert. Es ist ein Muss für Kliniker, die hämatologische Erkrankungen diagnostizieren und analysieren, darunter Hämatologen, Hämatopathologen, Onkologen, Pathologen und Mitarbeiter in diagnostischen Labors.

Autoren/Hrsg.

Ortolani, Claudio

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Hämatologie, Transfusionsmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Labormedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung

Inhaltsverzeichnis

Foreword to the Second Edition xi
by Michael J. Borowitz

Foreword to the First Edition xii
by Maryalice Stetler-Stevenson

Foreword to the First Edition xiii
by Bruno Brando

Preface to the Second Edition xv

Preface to the First Edition xvi

Abbreviations xvii

1 Antigens 1

Clustered (CD) Antigens

CD1 3

CD2 5

CD3 8

CD4 17

CD5 21

CD7 24

CD8 26

CD10 30

CD11b 35

CD11c 38

CD13 40

CD14 44

CD15 46

CD16 49

CD19 52

CD20 55

CD22 59

CD23 61

CD24 64

CD25 66

CD26 67

CD27 69

CD28 70

CD30 71

CD33 73

CD34 77

CD38 79

CD43 81

CD45 82

CD45 Isoforms 87

CD49 90

CD56 93

CD57 96

CD61 97

CD62L 98

CD64 99

CD65 101

CD66c 102

CD71 103

CD79 104

CD81 107

CD103 108

CD117 110

CD123 112

CD138 113

CD200 114

CD305 116

CD307 (IRTA) Antigen Family 117

CD371 118

Non clustered (or primarily known with other names) antigens Bcl-2 Protein 119

Chemokines and Chemokine Receptors 121

CRLF2 128

Cytotoxic Proteins 129

HLA-DR 130

Immunoglobulins 132

KIR, CD158 isoforms 136

Myeloperoxidase (MPO) 139

NG2 140

PCA-1 141

ROR1 141

SLAM Molecules and SLAM-associated Protein (SAP) 142

SOX11 144

T-cell Receptor (TCR) 145

Terminal Deoxy-nucleotidyl-transferase (TdT) 148

Toll-like Receptors (TLR) 150

VS38 151

ZAP-70 152

2 Diseases 155

Myeloproliferative neoplasms 157

Chronic myeloid leukemia (CML) 157

Myeloproliferative neoplasms other than CML 160

Chronic neutrophilic leukemia (CNL) 160

Polycythemia vera (PV) 160

Primary myelofibrosis (PMF) 160

Essential thrombocythemia (ET) 160

Chronic eosinophilic leukemia (CEL) 161

Mastocytosis 162

Acute mast-cell leukemia (AMCL) 162

Chronic mast-cell leukemia (CMCL) 163

Myelomastocytic leukemia (MML) 163

Myelodysplastic/myeloproliferative neoplasms 164

Chronic myelomonocytic leukemia (CMML) 164

Other myelodysplastic/myeloproliferative neoplasms and related conditions 167

Juvenile myelomonocytic leukemia (JMML) 167

Atypical CML bcr/abl negative (ACML) 167

RAS-associated autoimmune leukoproliferative disorder (RALD) 167

Myelodysplastic syndromes 168

Myeloid neoplasms with germline predisposition 171

Acute myeloid leukemias 172

AMLs with recurrent genetic anomalies 173

AMLs with chromosomal anomalies 173

AMLs with gene mutations 180

Relationships between genotype and phenotype in cases of AML not recognized as separate entities in WHO 2017 181

AMLs with myelodysplasia-related changes (AML-MRC) 182

AMLs not otherwise specified 182

AML with minimal differentiation 182

AML without maturation 183

AML with maturation 183

Acute myelomonocytic leukemia (AMMoL) 183

Acute monoblastic and monocytic leukemia (AMoL) 184

Pure erythroid leukemia (PEL) 185

Acute megakaryoblastic leukemia (AMKL) 186

Acute basophilic leukemia (ABL) 188

Myeloid proliferations associated with Down syndrome 188

Transient abnormal myelopoiesis (TAM) 189

AMLs in patients with Down syndrome 189

Blastic plasmacytoid dendritic cell neoplasm (BPDCN/PDCL) 189

Acute leukemias with ambiguous lineage attribution (ALAL) 192

Acute undifferentiated leukemias (AUL) 192

Mixed phenotype acute leukemias (MPAL) 192

Neoplastic diseases of B and T lymphatic precursors 194

B lymphoblastic leukemia/lymphoma, not otherwise specified (B-ALL/LBLnos) 195

B lymphoblastic leukemia/lymphoma with recurrent genetic anomalies 197

Relationsh

Über Autor(innen)

About the author

Claudio Ortolani is an expert in the area of diagnosis of hematological malig­­nancies. Now retired, Dr Ortolani was Consultant in the Department of Clinical Pathology at Venice General Hospital, Venice, Italy. He is one of the founding members of the Italian Society for Cytometric Cell Analysis (ISCCA), of whose board he is currently a member. He has taught and lectured internationally on how to use flow cytometry to aid in diagnosing hematological diseases.