Morel Molecular and Physiological Mechanisms of Muscle Contraction

Erscheinungsjahr 2015
ISBN: 978-1-4987-2503-3
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 350 Seiten

The Huxley model from the mid-twentieth century is a long-standing theory of the molecular mechanism by which muscles contract; it has become dogma. This model is also sometimes referred to as the Sliding Filament model. This book summarizes and evaluates current research of the Huxley model and proposes a hybrid model of muscle contraction. This new model will not replace the standard Huxley model of muscle contraction, but will modify it to reflect more recent experimental and laboratory findings.

Autoren/Hrsg.

Morel, Jean Emile

Fachgebiete

• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Anatomie

Inhaltsverzeichnis

Introduction. Materials and Methods. Analysis and Characteristics of Some Major Biophysical, Enzymological, and Physiological Phenomena in An Intact Unit Cell during Contraction (Isometric and Isotonic). New and Older Experimental Results and Interpretations. The General Features of the Hybrid Model. Quantitative Data and Calculations, Concerning Short Tetani Under Steady-State Isometric Contraction Conditions, Required for Quantification of the Hybrid Model. Fatigue in One Isometrically Contracting Half-Fiber from an Adult Frog, and in Intact and Traditionally Demembranated Fibers of Various Origins. Discussion Based Essentially on the Hybrid Model. Predictive and Explanatory Power of the Hybrid Model. Analysis of Various Problems. In Vitro Motility. A Critical Analysis of the Experimental Data and Their Interpretations. Movement of Cell Organelles. Conclusion.