Multiple Sclerosis

A Mechanistic View
Erscheinungsjahr 2015
ISBN: 978-0-12-800763-1
Verlag: Elsevier Science

Buch, Englisch, 538 Seiten, Format (B × H): 158 mm x 236 mm, Gewicht: 1000 g

Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS.

The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS.

It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study.

Zielgruppe

Researchers and graduate students in neurology, neuroscience, neurosurgery; internists and researchers in neuroinflammation and neuroimmunology

Autoren/Hrsg.

Minagar, Alireza

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Innere Medizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Neurochirurgie

Inhaltsverzeichnis

- Clinical manifestations of multiple sclerosis: An overview
- Novel Therapies for Multiple Sclerosis: A Mechanistic View
- Role of B cells in the pathogenesis of MS: Mechanisms of action
- Role of CD4+ T cells in the pathophysiology of MS
- GM-CSF in Central Nervous System Autoimmunity
- Role of cytokine-mediated crosstalk between T cells and non-immune cells in the pathophysiology of multiple sclerosis
- Vitamin D: role in pathogenesis of Multiple Sclerosis
- Role of genetic factors in pathogenesis of MS
- Neuropathology of multiple sclerosis
- Pathophysiology of acute disseminated encephalomyelitis
- Pathophysiology of experimental autoimmune encephalomyelitis
- Pathophysiology of optic neuritis
- Neurodegeneration and Remyelination in Multiple Sclerosis
- Mechanisms of action of Glatiramer Acetate in the treatment of multiple sclerosis
- Mechanism of Action of Interferon Beta in Treatment of Multiple Sclerosis
- Mechanisms of blood brain barrier disintegration in the pathophysiology of MS
- Mechanisms and potentials of Stem Cells in the treatment of Multiple Sclerosis: The unpaved path
- Role of neuroimaging in MS
- Pathophysiology of Lymphatic Drainage of the Central Nervous System. Implications for the Pathophysiology of Multiple Sclerosis

Über Autor(innen)

Minagar, Alireza
Dr. Minagar is a Professor of Neurology at LSU Health Sciences Center in Shreveport, Louisiana. He's a certified Physician Investigator by Association of Clinical Research Professionals, member of the editorial board of Future Neurology, Neurological Research, and Alzheimer's Disease Research Board. Dr. Minagar is the author of 231 journal articles and 33 book chapters, and editor of 10 books.