Miller Ion Channel Reconstitution

Erscheinungsjahr 2013
ISBN: 978-1-4757-1361-9
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 577 Seiten, eBook

Zielgruppe

Research

Autoren/Hrsg.

Miller, C.

Inhaltsverzeichnis

I. Basics.- 1 The Physical Nature of Planar Bilayer Membranes.- 2 Ion Channel Electrostatics and the Shapes of Channel Proteins.- 3 Superoxide Dismutase as a Model Ion Channel.- 4 Single-Channel Enzymology.- 5 How to Set Up a Bilayer System.- 6 Fusion of Liposomes to Planar Bilayers.- 7 Incorporation of Ion Channels by Fusion.- II. Nicotinic Acetylcholine Receptor.- 8 The Reconstituted Acetylcholine Receptor.- 9 Immunologic Analysis of the Acetylcholine Receptor.- 10 Function of Acetylcholine Receptors in Reconstituted Liposomes.- III. Sodium Channel.- 11 Skeletal Muscle Sodium Channels: Isolation and Reconstitution.- 12 Reconstitution of the Sodium Channel from Electrophorus electricus.- 13 The Reconstituted Sodium Channel from Brain.- 14 Gating of Batrachotoxin-Activated Sodium Channels in Lipid Bilayers.- 15 Ion Conduction Through Sodium Channels in Planar Lipid Bilayers.- 16 Blocking Pharmacology of Batrachotoxin-Activated Sodium Channels.- IV. Other Channels in Model Membranes.- 17 The Large Calcium-Activated Potassium Channel.- 18 The Sarcoplasmic Reticulum Potassium Channel: Lipid Effects.- 19 Characterization of Dihydropyridine-Sensitive Calcium Channels from Purified Skeletal Muscle Transverse Tubules.- 20 Calcium Channels.- 21 Phosphorylation of a Reconstituted Potassium Channel.- 22 Voltage Gating in VDAC: Toward a Molecular Mechanism.- 23 Analysis and Chemical Modification of Bacterial Porins.