Mamula / Kelsen / Grossman Pediatric Inflammatory Bowel Disease

Fourth Auflage 2023
ISBN: 978-3-031-14744-9
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 861 Seiten, eBook

The latest edition of this essential text provides a comprehensive overview of the unique pediatric issues of inflammatory bowel disease. Through new and thoroughly revised chapters, the volume features updates on all aspects of etiology, diagnosis, and treatment, with an emphasis on recent understanding of pharmacokinetics and the utilization of cutting edge therapeutic monitoring to maximize efficacy of medical management. The new edition also highlights newer, recently approved drugs, emerging therapies, and the most recent recommendations regarding post-operative management for patients who ultimately require surgery.  Written by experts in the field,  Pediatric Inflammatory Bowel Disease, Fourth Edition  is a valuable resource for both pediatric and adult gastroenterologists involved in the care of children with inflammatory bowel disease.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Mamula, Petar

Kelsen, Judith R.

Grossman, Andrew B.

Baldassano, Robert N.

Markowitz, Jonathan E.

Inhaltsverzeichnis

Etiology and Pathogenesis.-  Genetics of Inflammatory Bowel Diseases.- Immunologic Regulation of Health and Inflammation in the Intestine.- Cytokines and Inflammatory Bowel Disease.- The Gut Microbiota and Inflammatory Bowel Disease.- Immune Dysregulation Associated with Very Early-Onset Inflammatory Bowel Disease.-  Epidemiology and Clinical Features.-  The Epidemiology of Pediatric Inflammatory Bowel Disease.- The Natural History of Crohn Disease in Children.- Natural History of Ulcerative Colitis in Children.- Pediatric Inflammatory Bowel Disease – Unclassified.- Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease.- Liver Disease in Pediatric Inflammatory Bowel Disease.- Growth Impairment in Pediatric Inflammatory Bowel Disease.- Inflammatory Bowel Diseases and Skeletal Health.- Puberty and Pediatric-Onset Inflammatory Bowel Disease.- Classification of Pediatric Inflammatory Bowel Disease.-  Diagnosis.-  The History andPhysical Exam.- Differential Diagnosis of Inflammatory Bowel Disease.- Laboratory Evaluation of Inflammatory Bowel Disease.- Fecal Markers in Inflammatory Bowel Disease.- Radiologic Evaluation of Pediatric Inflammatory Bowel Disease.- Endoscopy and Inflammatory Bowel Disease.- The Pathology of Chronic Inflammatory Bowel Disease.- Capsule Endoscopy in Pediatric Inflammatory Bowel Disease.- Bone Health in Pediatric Inflammatory Bowel Disease.-  Medical Therapy.-  5-Aminosalicylate Therapy.- Antibiotic Therapy.- Nutritional Management of Inflammatory Bowel Disease.- Corticosteroid Therapy.- 6-Mercaptopurine Therapy.- Methotrexate.- Infliximab Therapy for Pediatric Crohn’s Disease and Ulcerative Colitis.- Anti-TNF Therapies Other Than Infliximab for the Treatment of Pediatric Inflammatory Bowel Disease.- Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease.- New Non-anti-TNF-a Biological Therapies for the Treatment of Inflammatory Bowel Disease.- Medical Treatment of Perianal Crohn’s Disease Fistulae Treatment of Perianal Crohn’s Disease.- Treatment of Acute Severe Ulcerative Colitis.- Dietary Therapies for Inflammatory Bowel Disease.- Integrative Health Therapies for Pediatric IBD.-  Surgical Therapy.-  Management of Intraabdominal Complications of Inflammatory Bowel Disease.- Surgical Management of Crohn Disease in Children.- Surgical Treatment of Ulcerative Colitis.- Postoperative Surveillance and Management of Crohn’s Disease.- Perioperative Immunosuppression in Inflammatory Bowel Disease.- Pouchitis and Pouch-Related Complications.- Title to come.-  Research.-  Clinical Indices for Pediatric Inflammatory Bowel Disease Research.- Clinical Trials (Clinical Perspective).- Global Regulatory Industry Perspective of Clinical Trials.-  Special Considerations.-  Infectious Complications of Pediatric Inflammatory Bowel Disease.- Psychological Aspects of Inflammatory Bowel Disease in Children and Adolescents.- Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease.- Irritable Bowel Syndrome and Functional GI Disorders in Inflammatory Bowel Disease.- Inflammatory Bowel Disease in Pregnancy.- Pediatric Inflammatory Bowel Disease Care in Low and Middle-Income Countries.- Immunizations in The Child with Inflammatory Bowel Disease.- Colitis-Associated Cancers.- Quality Improvement in Inflammatory Bowel Disease.- Fostering Self-Management and Patient Activation.- Advocacy for Pediatric Patients with Inflammatory Bowel Disease.- Advocacy for Pediatric Patients with Inflammatory Bowel Disease.- Transition from Pediatric to Adult Care.

Über Autor(innen)

Petar Mamula, MDDivision of GI, Hepatology & Nutrition The Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine at the University of Pennsylvania Philadelphia, PAUSA Andrew B. Grossman, MDDivision of GI, Hepatology & Nutrition Co-Director, Center for Pediatric Inflammatory Bowel DiseaseThe Children's Hospital of Philadelphia Associate Professor of Clinical Pediatrics Perelman School of Medicine at the University of PennsylvaniaPhiladelphia, PAUSA  Robert N. Baldassano, MDDivision of GI, Hepatology & Nutrition Director, Center for Pediatric Inflammatory Bowel Disease The Children's Hospital of Philadelphia Professor of Pediatrics Perelman School of Medicine at the University of PennsylvaniaPhiladelphia, PAUSA Judith R. Kelsen, MDDivision of GI, Hepatology & Nutrition The Children's Hospital of Philadelphia Assistant Professor of Pediatrics Perelman School of Medicine at the University of PennsylvaniaPhiladelphia, PAUSA Jonathan E. Markowitz, MD, MSCE, NASPGHAN-F Pediatric GastroenterologyPrisma Health Children’s Hospital–Upstate Professor and Vice Chair for Academic AffairsDepartment of PediatricsUniversity of South Carolina School of Medicine–Greenville200 Patewood Drive, A-140Greenville, SC  29615 Petar Mamula, MD, is a board certified Pediatric Gastroenterologist and Director of the Kohl's GI Nutrition and Diagnostic Center at Children's Hospital of Philadelphia. Heis also Co-Director of the Center for Digestive, Liver and Pancreatic Medicine, a CHOP/Penn collaborative program. Andrew B. Grossman, MD, is a pediatric gastroenterologist in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia. He is the co-director of CHOP's Center for Pediatric Inflammatory Bowel Disease. Robert N. Baldassano, MD, is a Pediatric Gastroenterologist and Director of the Center for Pediatric Inflammatory Bowel Disease at Children’s Hospital of Philadelphia. Dr. Baldassano’s research focuses on children who have inflammatory bowel diseases, and he oversees a large team of researchers at CHOP working to translate discoveries in the laboratory into direct patient care for children. One promising area of current research involves investigating the intestinal microbiomes of children with inflammatory bowel diseases. Judith R Kelsen, MD, is Program Director of the Very Early Onset Inflammatory Bowel Disease (VEO-IBD) Clinic and an Attending Physician in the Division of Gastroenterology, Hepatology and Nutrition at Children's Hospital of Philadelphia. Jonathan Markowitz, M.D, served on faculty at the Children's Hospital of Philadelphia for approximately 5 years before he joined Greenville Children's Hospital in 2006, where he has served as division chief of pediatric gastroenterology for the last 6 years. He is a clinical professor of pediatrics at USC School of Medicine-Greenville. Dr. Markowitz' research interests include eosinophilic esophagitis and inflammatory bowel disease. He has authored numerous articles and has lectured nationally and internationally. He is co-editor of Eosinophilic Esophagitis and Pediatric Inflammatory Bowel Disease. Dr. Markowitz has been featured in local and national media.