Novel Membrane Emulsification

Principles, Preparation, Processes, and Bioapplications
1. Auflage 2023
ISBN: 978-3-527-34881-7
Verlag: Wiley-VCH GmbH

Buch, Englisch, 368 Seiten, Format (B × H): 173 mm x 246 mm, Gewicht: 862 g

Novel Membrane Emulsification

Comprehensive resource presenting state-of-the-art of membrane emulsification technology, from principle to practice, with focus on biomedical applications

Novel Membrane Emulsification: Principles, Preparation, Processes, and Bioapplications provides comprehensive coverage of membrane emulsification technology by summarizing the principle, preparation, and bioapplications through utilizing uniform particle size, introducing recent development in preparation and applications in the controlled release and delivery of protein/peptide, anticancer drugs and vaccines, and in the bioseparation media and cell culture carriers, and discussing direct, rapid, and rotary membrane emulsification equipments.

Novel Membrane Emulsification includes information on: - Preparation of hydrophobic microspheres from O/W emulsion, hydrophilic microspheres from W/O emulsion, and microcapsules/composite microspheres from double emulsions, covering preparation from monomer and preformed polymer systems
- Preparation of small particles by rapid membrane emulsification process
- Applications of uniform particles in sustained release of protein/peptide drugs, covering strategies to improve encapsulation efficiency and maintain bioactivity of drugs
- Applications of uniform particles in anticancer drug and vaccine delivery including personalized therapeutic vaccine
- Applications of uniform particles in protein separation, covering uniform agarose microsphere for protein separation and super-porous microsphere for vaccine separation

Novel Membrane Emulsification is an essential resource for scientists and researchers in multiple fields, particularly chemistry, chemical engineering, and materials science, to advance this technique and produce novel materials with controlled characteristics. The text is also a valuable learning resource for biomedical science and bioengineering researchers and students.

Autoren/Hrsg.

Ma, Guanghui

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Chemische Verfahrenstechnik
• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Verfahrenstechnik, Chemieingenieurwesen

Inhaltsverzeichnis

CHAPTER 1 MEMBRANE EMULSIFICATION PROCESS: PRINCIPLE AND MODEL
1.1 Introduction
1.2 Cross-Flow Membrane Emulsification
1.3 Premix Membrane Emulsification
1.4 Summary
CHAPTER 2 PREPARATION OF HYDROPHOBIC MICROSPHERES FROM O/W EMULSION
2.1 Introduction
2.2 Preparation from Monomer System
2.3 Preparation from Performed Polymer System
2.4 Morphology Control of Microspheres
2.5 Summary
CHAPTER 3 PREPARATION OF HYDROPHILIC POLYMER MICROSPHERES FROM W/O EMULSION
3.1 Introduction
3.2 Membrane Modification and Preparation
3.3 Preparation Microparticles from Monomer System
3.4 Preparation Microparticles from Preformed Polymer System
3.5 Other Hydrophilic Microspheres Prepared by Membrane Emulsification
3.6 Summary
CHAPTER 4 PREPARATION OF UNIFORM MICROCAPSULES AND MICROSPHERES FROM W/O/W DOUBLE EMULSION
4.1 Introduction
4.2 Preparation of Uniform Microcapsules
4.3 Preparation of Composite Microspheres
4.4 Summary
CHAPTER 5 RAPID MEMBRANE EMULSIFICATION PROCESS FOR PREPARATION OF SMALL MICROSPHERES
5.1 Introduction
5.2 Preparation of Hydrophobic Microspheres from O/W Emulsion
5.3 Preparation of Hydrophilic Microspheres From W/O Emulsion
5.4 Preparation of Microcapsule from Double Emulsion
5.5 Summary
CHAPTER 6 APPLICATIONS OF UNIFORM PARTICLES IN SUSTAINED RELEASE OF DRUGS
6.1 Introduction
6.2 Synthetic Polymer (PLA, PLGA, PELA)
6.3 Natural Polymer (Polysaccharide) Chitosan
6.4 Summary
CHAPTER 7 APPLICATIONS OF UNIFORM PARTICLES FOR TARGETED DELIVERY OF ANTICANCER DRUGS
7.1 Introduction
7.2 Influence of Physical and Chemical Particle Properties on Antitumor Efficacy
7.3 Classical Strategies for Targeting Tumor Tissues
7.4 Novel Biomimetic Delivery Strategies
7.5 Summary
CHAPTER 8 APPLICATIONS OF UNIFORM PARTICLES IN VACCINE FORMULATIONS
8.1 Introduction
8.2 Adjuvant and Delivery System: Assembling the Vaccine Components
8.3 Physicochemical Traits for the Enhanced Vaccination
8.4 Connecting the dots: Strengthening on the Multi-Scale Delivery of Vaccines
8.5 Summary
CHAPTER 9 APPLICATIONS OF UNIFORM MICROSPHERES AND SUPER-POROUS MICROSPHERES IN BIOCHEMICAL ENGINEERING
9.1 Introduction
9.2 Uniform Microspheres for Chromatographic Media
9.3 Super-Porous Microspheres for Vaccine Separation
9.4 Uniform Microspheres for Cell Culture Carriers
9.5 Summary
CHAPTER 10 MEMBRANE EMULSIFICATION EQUIPMENT AND INDUSTRIALIZATION
10.1 Introduction
10.2 Cross-Flow Membrane Emulsification Equipment
10.3 Premix Membrane Emulsification Equipment
10.4 Rotary Membrane Emulsification Equipment
10.5 Industrialization - Case Report
10.6 Summary

Über Autor(innen)

Guanghui Ma is Professor and Director of State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences (CAS). Having obtained her Ph.D degree from Tokyo Institute of Technology, Japan, she started her academic career at Tokyo University of Agriculture and Technology as Assistant Professor (1994). She moved to Institute of Process Engineering, CAS as a Full Professor in 2001. She was selected as an academician of CAS in 2021. Her awards include Outstanding Contribution Award from Federation of Biotechnology (AFOB) and the Second-class prize of National Invention Award.