Langner / Ansorge Cellular Peptidases in Immune Functions and Diseases 2

Erscheinungsjahr 2006
ISBN: 978-0-306-46826-1
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 477, 522 Seiten, eBook

Reihe: Advances in Experimental Medicine and Biology

Zielgruppe

Research

Autoren/Hrsg.

Langner, Jürgen

Ansorge, Siegfried

Inhaltsverzeichnis

Membrane Ectopeptidases with Influence on Immune Functions.- Review: The Role of Membrane Peptidase in Immune Functions.- Structure and Function of Aminopeptidase N.- Modulation of WNT-5At Eexpression by Actinonin: Linkage of APN to the WNT-Pathway?.- Enzymatic Activity Is Not A Precondition For The Intracellular Calcium Increase Mediated By mAbs Specific For Aminopeptidase N/CD13.- Transforming Growth Factor-? Increases the Expression of Aminopeptidase N/CD13 mRNA and Protein in Monocytes and Monocytic Cell Lines.- Cell-Cell Contact Between Lymphocytes and Fibroblast-Like Synovioctyes Induces Lymphocytic Expression of Aminopeptidase n/cd13 and Results in Lymphocytic Activation.- Natural Substrates of Dipeptidyl Peptidase IV.- Relating Structure to Function in the Beta-Propeller Domain of Dipeptidyl Peptidase IV.- Development of a Tertiary-Structure Model of the C-Terminal Domain of DPP IV.- Post Proline Cleaving Peptidases Having DP IV Like Enzyme Activity.- A New Type of Fluorogenic Substrates for Determination of Cellular Dipeptidyl Peptidese IV (DP IV/CD26) Activity.- Potent Inhibitors of Dipeptidyl Peptidase iv and Their Mechanisms of Inhibition.- N-Terminal HIV-1 Tat Nonapeptides as Inhibitors of Dipeptidyl Peptidase IV. Conformational Characterization.- Signal Transduction Events Induced or Affected by Inhibition of the Catalytic Activity of Dipeptidyl Peptidase IV (DP IV, CD26).- Specific Inhibitors of Dipeptidyl Peptidase IV Suppress mRNA Expression of DP IV/CD26 and Cytokines.- Dipeptidyl Peptidase IV in Inflammatory CNS Disease.- Dipeptidyl Peptidase IV (CD26): Role in T Cell Activation and Autoimmune Disease.- Effects of Nonapeptides Derived From the N-terminal Structure of Human Immunodeficiency Virus-1 (HIV-1) Tat on Suppression of CD26-Dependent T CellGrowth.- DNA Synthesis in Cultured Human Keratinocytes and Hacat Kerationcytes is Reduced by Specific Inhibition of Dipeptidyl Peptidase IV (CD26) Enzymatic Activity.- Attractin: A Cub-Family Protease Involved in T Cell-Monocyte/Macrophage Interactions.- Analogs of Glucose-Dependent Insulinotropic Polypeptide With Increased Dipeptidyl Peptidase IV Resistance.- Dipeptidyl Peptidase IV (DPP IV, CD26) In Patients With Mental Eating Disorders.- The Membrane-Bound Ectopeptidase CPM as a Marker Of Macrophage Maturation in vitro And in vivo.- Matrix Metalloproteinases (MMP-8, -13 and -14) Interact with the Clotting System and Degrade Fibrinogen and Factor XII (Hagemann Factor).- The Neprilysin Family in Health and Disease.- Cellular Endopeptidases: New Cathepsins; Results from Knock-out-mice; Regulatory Aspects.- Review: Novel Cysteine Proteases of the Papain Family.- Development and Validation of Homology Models of Human Cathepsins K, S, H, and F.- The Function of Propeptide Domains of Cysteine Proteinases.- Human Cathepsins W and F form A New Subgroup of Cathepsins that is Evolutionary Separated from the Cathepsin B- and L-Like Cysteine Proteases.- Cathepsin K Expression in Human Lung.- Expression of Cathepsins B and L in Human Lung Epithelial Cells is Regulated by Cytokines.- Functions of Cathepsin K in Bone Resorption.- Ceramide as an Activator Lipid of Cathepsin D.- Human Cathepsin X.- A Novel Proteolytic Mechanism for Termination of the Ca2+ Signalling Evoked by Proteinase-Activated Receptor-1 (PAR-1) in Rat Astrocytes.- Natural and Synthetic Inhibitors of The Tumor-Associated Serine Protease Urokinase-Type Plasminogen Activator.- Processing of Interleukin-18 by Human Vascular Smooth Muscle Cells.- Peptidases and Peptidase Inhibitors in Pathogensis of Diseases.- Review:Peptidases and Peptidase Inhibitors in the Pathogenesis of Diseases.- The Role of Proteolysis in Alzheimer’s Disease.- Observing Proteases in Living Cells.- The Role of Cysteine Proteases in Intracellular Pancreatic Serine Protease Activation.- Peptidases in the Asthmatic Airways.- Inactivation of Interleukin-6 by Neutrophil Proteases at Sites of Inflammation.- Antisense Inhibition of Cathepsin Bina Human Osteosarcoma Cell Line.- Protease-Protease Inhibitor Balance in the Gastric Mucosa.- The Role of Bacterial and Host Proteinases in Periodontal Disease.- Multifunctional Role of Proteases in Rhumatic Diseases.- Evidence of Proteolytic Activation of Transforming Growth Factor ? in Synovial Fluid.- Matrix Metalloproteinases and Tace Play A Role in The Pathogenesis of Endometriosis.- Influence of Proliferation, Differentiation and Dedifferentiation Factors on the Expression of the Lysosomal Cysteine Proteinase Cathepsin L (CL) in Thyroid Cancer Cell Lines.