Taurine 8

Volume 1: The Nervous System, Immune System, Diabetes and the Cardiovascular System
2013
ISBN: 978-1-4899-8621-4
Verlag: Springer

Buch, Englisch, 454 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 6964 g

Taurine 8 represents the combined efforts of investigators on the roles of the amino acid taurine on human health and disease. The chapters covered in this book are directly derived from presentations of the contributors at the 18th International Taurine Meeting held in Marrakech, Morocco in April 2012. The purpose of this book is to disseminate current findings on taurine's contribution in several organ systems. This book covers the following topics: Taurine in the Nervous System, Taurine in the Immune System, Taurine and Diabetes, and Taurine and the Cardiovascular System. Dr. Abdeslem El Idrissi, College of Staten Island and Dr. William L’Amoreaux, College of Staten Island,  were co-chairs of the Organizing Committee for the meeting.

 
Data presented at this meeting provided compelling evidence that taurine is not only cytoprotective in cardiomyocytes, but also is a potent GABA agonist, whereby it can facilitate vasodilation of conducting arteries. Taurine conjugates, such as taurine chloramine, may protect cells from oxidative stress via increased HO-1 expression. In adult rodents, taurine has a potent effect on plasma glucose levels, likely through the release of insulin in pancreatic beta cells. As a potential neurotransmitter, taurine is known to work via the GABAergic system, but current research presented at this meeting suggest that taurine may interact with glutamate and serotonin receptors as well. Data are also presented to demonstrate the protective roles of taurine on neurons in neuroblastoma. Perhaps the most important and exciting presentation is the role of taurine and alcohol: the combination may be lethal. Data are also presented at this meeting of the potential role taurine may have as an adjuvant treatment with cisplatin in chemotherapy.

Zielgruppe

Research

Autoren/Hrsg.

L'Amoreaux, William J.

El Idrissi, Abdeslem

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Ernährungsmedizin, Diätetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Diabetologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

There is a Taurine-Linked Disease Known As Melas.- Taurine And Hearty Topics.- Taurine Regulation Of Peripheral Hemodynamics.- Regulation Of Taurine Release By Neurotransmitter Receptors.- Neuropsychopharmacological Actions Of Taurine.- Neuro-Protective Mechanism Of Taurine – Role Of Endoplasmic Reticulum.- Differential Regulation Of Taut By Vitamin D3 And Retinoic Acid Via Vdr/Rxr In Llc-Pk1 And Mcf-7 Cells.- Are Taurine Haloamines (Taucl And Taubr) Good Candidates For The Treatment Of Biofilm–Associated Infections?.- Comparative Evaluation Of Taurine And Thiotaurine As Protectants Against Experimental Diabetes-Induced Nephropathy In A Rat Model.- The Mechanism of Taurine Protection against Endoplasmic Reticulum Stress in Stroke Related Conditions in Primary Neuronal Cell Culture.- Direct interaction of taurine with the NMDA glutamate receptor sub-type via multiple mechanisms.- Perinatal taurine exposure affects patterns of autonomic nerve activity in adult male rats.- Lethality of taurine and alcohol co-administration in 7-day-old, adult and old mice.- Metabotropic effect of taurine regulation of potassium channels via 5-HT2A serotonin receptors.- Changes in gene expression at inhibitory synapses in response to taurine treatment.- Effects of Acute vs. Chronic Taurine Treatment on Context Fear Aversive Conditioning in Mice.- Taurine exerts robust protection against hypoxia and glucose deprivation in human neuroblastoma cell culture.- Perinatal taurine supplementation affects neural control of arterial pressure via estrogen receptors in adult female rats.- Gender specific effects of taurine on cardiovascular function.- Taurine affects release of insulin and GABA in Hit-T15 ß cell line via calcium flux.- Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long duration of diabetes.- Preventive Roles of Taurine in Alloxan-Induced Diabetes.-Renin-angiotensin system and estrogen attenuates glucose-insulin dysregulati