Electrical Dynamics of the Dendritic Space

Erscheinungsjahr 2009
ISBN: 978-0-521-89677-1
Verlag: Cambridge University Press

Buch, Englisch, 224 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 594 g

The authors explain how the whole dendritic arborization contributes to the generation of various output discharges and elucidate the mechanisms of the transfer function of all dendritic sites. Their alternative modelling approach to conventional models introduces the notion of a functional dendritic space, and they have concentrated on a detailed spatial description of the electrical states at all dendritic sites when the dendrites operate. By analyzing the electrical dendritic space in which all the signals are processed, the authors provide tools to explore the spatial dimension of the transient events well known by electrophysiologists. They demonstrate the mechanisms by which the operating dendrites decide how, in fine, the distributed synaptic inputs generate final various output discharges. Their approach reveals the mechanisms by which individual dendritic geometry determines the sequence of action potentials that is the neuronal code. An accompanying NeuronViewer allows readers to monitor the simulation of operating dendritic arborization.

Autoren/Hrsg.

Korogod, Sergiy Mikhailovich

Ty¿-Dumont, Suzanne

Tyc-Dumont, Suzanne

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Naturwissenschaften Biowissenschaften Biowissenschaften Neurobiologie, Verhaltensbiologie
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik

Inhaltsverzeichnis

1. Definition of the neuron; 2. 3D geometry of dendritic arborizations; 3. Basics in bioelectricity; 4. The cable theory and the dendrites; 5. Voltage transfer over the dendrites; 6. Current transfer over dendrites; 7. Electrical structure of an artificial dendritic path; 8. Electrical structure of a bifurcation; 9. Geography of the dendritic space; 10. Electrical structures of biological dendrites; 11. Electrical structure of the whole arborization; 12. Electrical structures in the 3D dendritic space; 13. Dendritic space as coder of the temporal output patterns; 14. Concluding remarks.

Über Autor(innen)

Korogod, Sergiy Mikhailovich
Sergey Korogod is Professor and Head of Department of Experimental Physics at the Dniepropetrovsk National University, and Head of Dniepropetrovsk Division, International Center for Molecular Physiology at the National Academy of Science of the Ukraine.

Tyc-Dumont, Suzanne
Suzanne Tyc-Dumont is Director of Research Emeritus at CNRS, Paris. She has been active since the early 1980s in the promotion of the notion of the dendritic shape as one of the most critical factors in the understanding of dendritic processing, and introduced computational tools for the quantification of the geometry of dendritic arborizations in her laboratory.