Katzman / Bick Alzheimer Disease: The Changing View

The Changing View
1. Auflage 2000
ISBN: 978-0-08-052708-6
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 387 Seiten, Web PDF

This book details how 'Alzheimer Disease' went from being an obscure neurologic diagnosis to a household word. The words of those responsible for this revolution are the heart of this book. Dr. Robert Katzman and Dr. Katherine Bick, leaders in Alzheimer research and policy making, interview the people responsible for this awakening of public consciousness about AlzheimerDisease from 1960 to 1980. They speak with the scientists, public health officials, government regulators, and concerned relatives and activists responsible for taking this neurodegenerative disease out of the 'back wards' through the halls of Congress, and on to the front page. The reader will learn how the explosive increase in research funding and public awareness came about, how physicians and psychiatrists established diagnostic criteria, how drugs were developed that offer hope for sufferers, and how the Alzheimer's Association was born.* Written in the words of those responsible for the widespread recognition of this neurodegenerative disease* The authors are recognised as leaders in Alzheimer research and policy making

Robert Katzman, M.D., a member of the Institute of Medicine of the National Academy of Sciences, is the recipient of numerous scientific awards. He has enjoyed a long career as a physician, neuroscientist, and policy maker, serving on the faculty at Albert Einstein University in New York and currently at the University of California, San Diego. His research has centered on the epidemiology of aging and Alzheimer disease, and his seminal editorial in 1976 sparked the NIH to hold the first conference on the subject. Dr. Katzman has been a catalyst in the formation of the Alzheimer's Association.

Autoren/Hrsg.

Katzman, Robert

Bick, Katherine

Inhaltsverzeichnis

1;Front Cover;1
2;Alzheimer Disease: The Changing View;4
3;Copyright Page;5
4;Contents;8
5;Preface;12
6;Chapter I. Setting the Stage;16
7;Chapter 2. The Pioneers;26
7.1;The Ultrastructure of AD;26
7.2;Cognitive Decline in the Elderly and AD Pathology — The First Prospective Study: Newcastle;61
8;Chapter 3. The Need For Care;112
8.1;The Impact on Families;112
8.2;Designing the First Special Care Unit;129
9;Chapter 4. Understanding the Biology of AD;142
9.1;Experimental Models;142
9.2;Genetics;165
10;Chapter 5. The Cholinergic Story: Hope for the Patient and Family;182
10.1;Clues and Chemical Leads: Scopolamine Impairs Cognition;182
10.2;The Loss of Cholinergic Markers in the AD Brain;194
11;Chapter 6. Improving the Accuracy of Diagnosis;226
12;Chapter 7. The Impact of AD and Society's Response;252
12.1;Demography;252
12.2;Public Health Impact;267
12.3;The National Institutes of Health Respond;287
12.4;The Rise of the Alzheimer's Association;327
13;Chapter 8. The Next Act;368
14;Index;394