Iglic¿ / Igli?? Advances in Planar Lipid Bilayers and Liposomes

1. Auflage 2010
ISBN: 978-0-12-381014-4
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: 6 - ePub Watermark

E-Book, Englisch, Band Volume 11, 208 Seiten

Reihe: Advances in Planar Lipid Bilayers and Liposomes

Advances in Planar Lipid Bilayers and Liposomes, Volume 11, includes invited chapters on a broad range of topics, covering both of the main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results of their own research groups in this exciting multidisciplinary field. This volume addresses the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the further development of this interdisciplinary field worldwide. - Incorporates contributions from newcomers and established and experienced researchers - Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives - Serves as an indispensable source of information for new scientists

Autoren/Hrsg.

Iglic¿, AleS

Igli??, Ale?

Inhaltsverzeichnis

1;Front Cover;1
2;Advances in Planar Lipid Bilayers and Liposomes;4
3;Copyright Page;5
4;Contents;6
5;Preface;10
6;Contributors;12
7;Chapter One: Phospholipid Demixing: Molecular Interpretation of Lipid Droplet Biogenesis;16
7.1;1. Introduction;17
7.2;2. Theoretical Model;19
7.3;3. Molecular Interpretation;26
7.4;4. Results;27
7.5;5. Discussion;34
7.6;6. Summary;39
7.7;Acknowledgments;40
7.8;References;40
8;Chapter Two: Voltage- and Current-Clamp Methods for Determination of Planar Lipid Bilayer Properties;44
8.1;1. Introduction;45
8.2;2. Measurement Systems;47
8.3;3. Methods for Determination of Planar Lipid Bilayer Properties;64
8.4;4. Conclusions;75
8.5;Appendix A. Review of Measuring Systems;76
8.6;Appendix B. Review of Measured Properties on Planar Lipid Bilayer;79
8.7;References;81
9;Chapter Three: Stable and Reproducible Bilayer Lipid Membranes Based on Silicon Microfabrication Techniques;86
9.1;1. Introduction;87
9.2;2. Reproducible BLM Formation Studied by Infrared Absorption Spectroscopy (IRAS);88
9.3;3. Formation of Stable Free-Standing BLMs;93
9.4;4. Conclusion;99
9.5;References;99
10;Chapter Four: Formation of Planar Lipid Bilayer Membranes and Vesicles using Microfluidic Technology;102
10.1;1. Introduction;103
10.2;2. Planar Lipid Bilayer Membranes;103
10.3;3. Monodisperse Lipid Vesicles;108
10.4;4. Arraying Technology;112
10.5;5. Conclusions;114
10.6;Acknowledgments;114
10.7;References;114
11;Chapter Five: Spatial Variation of Permittivity near a Charged Membrane in Contact with Electrolyte Solution;116
11.1;1. Introduction;117
11.2;2. Orientation of Water Molecules near a Charged Membrane Surface;117
11.3;3. Excluded Volume Effect;123
11.4;4. Excluded Volume Effect and Orientation of Water Molecules;126
11.5;5. Phenomenological Model of Spatial Variation of Permittivity and the Membrane Surface Potential;133
11.6;6. Conclusions;138
11.7;References;140
12;Chapter Six: What Is the Difference Between a Supported and a Free Bilayer? Insights from Molecular Modeling on Different Scale;142
12.1;1. Introduction;143
12.2;2. Modeling of Lipid Bilayers;147
12.3;3. Observables for Characterization of Bilayer Systems in Molecular Modeling;151
12.4;4. Characteristics of Supported and Unsupported Bilayers;155
12.5;5. Influence of Corrugation;165
12.6;6. Conclusions and Outlook;166
12.7;Acknowledgments;167
12.8;References;168
13;Chapter Seven: X-ray and Neutron Scattering Studies of Lipid-Sterol Model Membranes;174
13.1;1. Introduction;175
13.2;2. Scattering Studies on Model Membranes;176
13.3;3. Influence of Sterols on the Structure and Phase Behavior of Lipid Bilayers;182
13.4;4. Fluid-Fluid Phase Separation in Raft Mixtures;193
13.5;References;198
14;Subject Index;202