Hollaender Radiation Protection and Recovery

International Series of Monographs on Pure and Applied Biology: Modern Trends in Physiological Sciences
1. Auflage 2013
ISBN: 978-1-4831-9477-6
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 398 Seiten, Web PDF

Modern Trends in Physiological Sciences, Volume 7: Radiation Protection and Recovery covers the biological, physiological, and biochemical methods created to protect living organisms from radiation damage. This book is composed of 12 chapters that evaluate the methods of protecting macromolecules in vitro against ionizing radiation damage. It addresses the degradation of polymethacrylic acid and the polymerization of vinyl monomers. Some of the topics covered in the book are the chemical protection to mammals against ionizing radiation; chemical protective agents; methods of protection and recovery in bacteria and fungi; and effect of cultural conditions and physiological state on radiosensitivity. Other chapters deal with the experimental modification of radiosensitivity and the role of phase state in inactivitation. These topics are followed by an analysis of the effect of the gaseous environment during irradiation. The chemical protection against inactivation and mutation is also presented. The last chapter is devoted to the environmental factors in radioresistance. The book can provide useful information to doctors, radiologists, students, and researchers.

Autoren/Hrsg.

Hollaender, Alexander

Inhaltsverzeichnis

1;Front Cover;1
2;Radiation Protection and Recovery;4
3;Copyright Page;5
4;Table of Contents ;6
5;Chapter 1. Introduction;8
6;Chapter 2. Protection of macromolecules in vitroagainst damage by ionizing radiations;10
6.1;I. INTRODUCTION;10
6.2;II. POSSIBLE MECHANISMS BY WHICH PROTECTIONCAN BE BROUGHT ABOUT;16
6.3;III. EXAMPLES OF PROTECTION AGAINST INDIRECT ACTION;24
6.4;IV. PROTECTION AGAINST DIRECT ACTION;39
6.5;V. RELATION OF PROTECTION AT THE MOLECULAR LEVELTO PROTECTION IN VIVO;46
6.6;LITERATURE CITED;48
7;Chapter 3. Chemical protection to mammalsagainst ionizing radiation;52
7.1;I. INTRODUCTIO;52
7.2;II. DESIGN OF EXPERIMENTS;54
7.3;III. CHEMICAL PROTECTIVE AGENTS;57
7.4;IV. MECHANISMS OF PROTECTION;78
7.5;LITERATURE CITED;82
8;Chapter 4. Protection and recovery in bacteriaand fungi;96
8.1;I. EFFECT OF CULTURAL CONDITIONS AND PHYSIOLOGICALSTATE ON RADIOSENSITIVITY;97
8.2;II. EXPERIMENTAL MODIFICATION OF RADIOSENSITIVITY;101
8.3;III. PROTECTION AGAINST MUTATIONS;112
8.4;IV. RECOVERY FROM RADIATION DAMAGE;114
8.5;V. RECOVERY FROM GENETIC DAMAGE;117
8.6;VI. GENERAL DISCUSSION OF PROTECTION AND RECOVERYIN BACTERIA AND FUNGI;119
8.7;LITERATURE CITED;121
9;Chapter 5. Protection and recovery of the cellfrom radiation damage;126
9.1;I. INTRODUCTION;126
9.2;II. MATERIALS AND TECHNIQUES;128
9.3;III. BIOLOGICAL FACTORS IN RADIORESPONSE;130
9.4;IV. ENVIRONMENTAL FACTORS IN RADIORESISTANCE;138
9.5;V. CONCLUSION;157
9.6;LITERATURE CITED;158
10;Chapter 6. Chromosome aberrations;166
10.1;I. INTENSITY AND FRACTIONATION;169
10.2;II. CENTPIFUGATION;170
10.3;III. STAGE SENSITIVITY;170
10.4;IV. EFFECT OF SPINDLE POISONS;170
10.5;V. ULTRAVIOLET RADIATION;171
10.6;VI. WATER CONTENT;171
10.7;VII. TEMPERATURE;172
10.8;VIII. CHEMICAL PROTECTION;172
10.9;IX. OXYGEN;173
10.10;X. CONCLUSION;181
10.11;LITERATURE CITED;182
11;Chapter 7. Protection and recovery fromionizing radiation: Mechanisms inseeds and roots;186
11.1;I. INTRODUCTION;186
11.2;II. EFFECTS OF IONIZING RADIATIONS ON ROOTS;187
11.3;III. EFFECTS OF IONIZING RADIATION ON SEEDS;202
11.4;LITERATURE CITED;214
12;Chapter 8. Genetical protection;223
12.1;I. INTRODUCTION;223
12.2;II. SPONTANEOUS MUTATIONS;224
12.3;III. INDUCED MUTATIONS;225
12.4;IV. CONCLUDING REMARKS;245
12.5;LITERATURE CITED;247
13;Chapter 9. Experimental treatment of acutewhole-body radiation injuryin mammals;253
13.1;I. INTRODUCTION;253
13.2;II. BASIC MECHANISMS IN ACUTE RADIATION DEATH;254
13.3;III. HISTORICAL RESUME;255
13.4;IV. ISOLOGOUS BONE MARROW;257
13.5;V. HOMOLOGOUS BONE MARROW;259
13.6;VI. HETEROLOGOUS BONE MARROW;261
13.7;VII. SHIELDING PROCEDURES;261
13.8;VII. SHIELDING PROCEDURES;261
13.9;VIII. RADIATION EFFECTS NOT INFLUENCED BYBONE MARROW THERAPY;262
13.10;IX. ACTION OF BONE MARROW;263
13.11;X. CELL TYPES RESPONSIBLE FOR REPOPULATION;269
13.12;XI. BONE MARROW CELL DOSE;270
13.13;XII. ROUTE OF INJECTION;272
13.14;XIII. TIME OF INJECTION;272
13.15;XIV. LOCALIZATION OF INJECTED CELLS;273
13.16;XV. AGE OF RECIPIENT;273
13.17;XVI. PRESERVATION AND TISSUE CULTURE OFBONE MARROW;274
13.18;XVII. AMOUNT AND TYPE OF IRRADIATION;275
13.19;XVIII. USE OF NONLIVING MATERIAL;277
13.20;XIX. FOREIGN BONE MARROW REACTION;280
13.21;XX. EXPERIMENTAL APPLICATIONS;289
13.22;XXI. CLINICAL APPLICATIONS;291
13.23;LITERATURE CITED;295
14;Chapter 10. Modification of delayed somaticeffects of ionizing radiation;316
14.1;I. INTRODUCTION;316
14.2;II. RADIOLOGICAL FACTORS;316
14.3;III. PHYSIOLOGICAL FACTORS;318
14.4;IV. HYPOXIA;319
14.5;V. SULFHYDRYL-CONTAINING COMPOUNDS;320
14.6;VI. POLYPHENOL DERIVATIVES;321
14.7;VII. PARTIAL-BODY SHIELDING;322
14.8;VIII. TRANSPLANTATION OF HEMOPOIETIC CELLS;323
14.9;CONCLUSION;325
14.10;CONCLUSION;325
14.11;LITERATURE CITED;325
15;Chapter 11. Effect of radiation onantibody formation;329
15.1;I. INTRODUCTION;329
15.2;II. SITE OF ANTIBODY FORMATION;330
15.3;III. THEORIES OF ANTIBODY FORMATION;332
15.4;IV. TEMPORAL RELATION BETWEEN ANTIGEN INJECTIONAND IRRADIATION;334
15.5;V. ANTIBODY RESPONSE DURING MAXIMUM DEPRESSIONPERIOD AFTER VARYING X-RAY DOSES;340
15.6;VI. EFFECT OF RADIATION ON THE RECOGNITION FACTOROF ANTIBODY-FORMING CELLS;344
15.7;VII· MODIFICATION OF THE IMMUNE MECHANISM OF ANIRRADIATED ANIMAL;347
15.8;VIII. LETHALLY X-RAYED ISOLOGOUS MICE AS IN VIVO TISSUECULTURES OF ANTIBODY-FORMING CELLS;355
15.9;IX. SUMMARY;358
15.10;LITERATURE CITED;359
16;Chapter 12. Photoreactivation;367
16.1;I. INTRODUCTION;367
16.2;II. GENERAL FEATURES;367
16.3;III. THE MECHANISM;378
16.4;IV. GENERAL REMARKS;387
16.5;LITERATURE CITED;388
17;INDEX;396