E-Book, Englisch, 461 Seiten
Reihe: Advances in Chromatography
E-Book, Englisch, 461 Seiten
Reihe: Advances in Chromatography
ISBN: 978-1-4398-4092-4
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
Highlights in this edition include:
- The hyphenation of liquid chromatography with mass spectrometry in order to determine oligonucleotide adducts as markers for cancer
- Glycoproteomics and the glycosylation of proteins, addressing biomarkers in different types of diseases
- Chiral separation, an important area particularly in the pharmaceutical industry, where the technique has been applied with varying results
- Ion-pairing chromatography and analyte retention
Conveying the most recent significant scientific developments in separation science, the book and its series are known for the authors’ clear presentation of topics and vivid illustrations. Accessible and engaging, this volume forms a solid foundation for the work of biochemists and analytical, organic, polymer, and pharmaceutical chemists at all levels of technical skill. Meticulously referenced, it will help fuel further research across a range of fields.
Zielgruppe
Analytical chemists, biochemists, and pharmaceutical scientists.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Retention Mechanism for Ion-Pair Chromatography with Chaotropic Reagents: From Ion-Pair Chromatography toward a Unified Salt Chromatography, T. Cecchi
Chronological Description of the Retention Modeling in IPC
Renewed Interest in Inorganic Ionic Additives in the RP-HPLC of Ionogenic Analytes
Stoichiometric Approaches to Chaotropic Chromatography
Development of the First Thermodynamic Theoretical Model of Salt Chromatography
Practical Impact of Chaotropic Chromatography
Urgent Research Needs and Suggestions
Mechanistic Aspects of Chiral Recognition on Protein-Based Stationary Phases, J. Haginaka
Basic Principles of Chiral Recognition on a Protein
Chiral Recognition Mechanism on Protein-Based Stationary Phases
List of Abbreviations
Mechanistic Aspects and Applications of Chiral Ligand-Exchange Chromatography, B. Natalini, R. Sardella, A. Macchiarulo, M. Marinozzi, E. Camaioni, and R. Pellicciari
Thermodynamic Enantioselectivity in CLEC Systems
Kinetic Enantioselectivity
Reciprocity of Chiral Recognition in CLEC Systems
Secondary Equilibria in CLEC Systems
Relevant Factors Influencing the Chromatographic Behavior of Amino Acids in CLEC
Covalently Bound Chiral Stationary Phases (B-CSPs)
Coated Chiral Stationary Phases (C-CSPs)
Chiral Mobile Phases (CMPs)
Computational Approaches in Chiral Ligand-Exchange Chromatography
List of Abbreviations
Glycosylation Analysis of Proteins, Proteoglycans, and Glycolipids Using Capillary Electrophoresis and Mass Spectrometry, A.D. Zamfir, C. Flangea, F. Altmann, and A. M. Rizzi
Pretreatment Strategies for Glycoconjugate Analysis
General Technical Considerations Regarding CE-MS Hyphenation and MS/MS of Oligosaccharides
Glycoproteins
Glycosaminoglycans
Glycolipids
Oligonucleotide Adducts as Biomarkers for DNA Damages: Analysis by Mass Spectrometry Coupled to Separation Methods, Q.Liao and P. Vouros
Analysis of DNA Adducts by Mass Spectrometry
Quantitative In Silico Analysis of the Specificity of Graphitized (Graphitic) Carbons, T. Hanai
Specificity of Graphitized Carbons
Calculation of Molecular Interaction Energy Values
Selectivity of Graphitized Carbon in Nonaqueous System
Selectivity of Graphitized Carbon Columns in Aqueous Phase
Stereo Selectivity of Graphitized Carbon
Synthesis of Graphitized Carbon for Chromatography
Applications
Application of Column-Switching Methods in HPLC for Evaluating Pharmacokinetic Parameters, H. J. Lee and K.–B. Kim
Applications of Column Switching
Principles of Column-Switching Technique
Column-Switching HPLC Configuration
Application of Column-Switching HPLC Method for Analysis of Compounds in Biological Matrices
Chromatographic Procedures in a Regulated Environment, T. P. Tougas
Application of Chromatography in Pharmaceutical Product Development and Commercialization
Validation of Analytical Procedures
Method Transfer
The Use of Novel Materials as Solid-Phase Extractors for Chromatographic Analysis, K. Pyrzynska
Bonded-Phase Silica Sorbents
Polymeric Materials
Carbonaceous Materials
Restricted Access Materials
Immunosorbents
Molecularly Imprinted Polymers
Thin-Layer and High-Performance Thin Layer Chromatographic Analysis of Biological Samples, J. Sherma and B. Fried
Materials and Techniques
Applications of TLC and HPTLC for Analysis of Biological Samples
Future Prospects
Index
