Diana / Cirrincione Biosynthesis of Heterocycles

From Isolation to Gene Cluster
1. Auflage 2015
ISBN: 978-1-118-96042-4
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 784 Seiten, E-Book

This book describes biosynthetic methods to synthesize heterocycliccompounds, offering a guide for the development of new drugs basedon natural products. The authors explain the role of naturalproducts in chemistry and their formation along with importantanalytical methods and techniques for working withheterocycles.
* Covers methods and techniques: isotopic labelling,enzymes and mutants, and pathway identification
* Provides a thorough resource of informationspecifically on heterocyclic natural products and their practicalbiosynthetic relevance
* Explains the role of natural products in chemistry andtheir formation
* Discusses gene cluster identification and the use ofbiogenetic engineering in pharmaceutical application

Autoren/Hrsg.

Diana, Patrizia

Cirrincione, Girolamo

Über Autor(innen)

Patrizia Diana is full Professor of Medicinal Chemistryat the University of Palermo. She is currently coordinator of theMedicinal and Biological Section of the Department of Science andTechnology: Chemical, Biological, and Pharmaceutical (STEBICEF);and is a member of the Italian Chemical Society and InternationalSociety of Heterocyclic Chemistry.
Girolamo Cirrincione is full Professor of MedicinalChemistry at the University of Palermo. He is a member of the DrugDiscovery Committee of the Pharmacology and Molecular Mechanisms(PAMM)Group of the European Organization for Research and Treatmentof Cancer; the Italian Chemical Society, where he is currentlyserving as President of the Medicinal Chemistry Division; and theInternational Society of Heterocyclic Chemistry, where he served as vice president for 2004-05