Androgens and Androgen Receptor

Mechanisms, Functions, and Clini Applications
2002
ISBN: 978-1-4020-7188-1
Verlag: Springer US

Buch, Englisch, 503 Seiten, HC runder Rücken kaschiert, Format (B × H): 160 mm x 241 mm, Gewicht: 1990 g

Androgen Receptors is the most comprehensive and up to date volume on the topic, including discussions of the basic mechanisms of androgen-androgen receptor actions, their roles in the androgen-related diseases, and their potential clinical applications.
Key topics covered include:

-The discovery and cloning of the androgen receptor;
-Androgen receptor coregulators;
-Androgen related genes and their consensus DNA response elements;
-Basic mechanism of action including functional analyses, cellular localization and phosphorylation studies;
-Cross-talk to other signal transduction systems;
-The recent connections of androgens to women's diseases, such as osteoporosis and ovarian cancer.

This book is of interest to students, basic scientists, and clinicians as both a study guide and reference of research in the androgen field. It could also be used as an advanced level text in endocrinology, urology, OBGYN, or oncology.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Chang, Chawnshang

Fachgebiete

• Medizin | Veterinärmedizin Veterinärmedizin Veterinärmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Gynäkologie, Geburtshilfe
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Physiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Dermatologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Urologie, Andrologie, Venerologie

Inhaltsverzeichnis

1. Androgen Biosynthesis and Degradation.- 2. Structural and Functional Analysis of the Androgen Receptor.- 3. Signal Transduction Pathways Modulate Androgen Receptor Transcriptional Activity.- 4. Androgen Receptor Interacting Proteins Co-Activators and Co-Repressors.- 5. Nongenomic Androgen Action.- 6. The Role of 5?-Reductase in Prostate Disease and Male Pattern Baldness.- 7. Natural Products and Environmental Androgens/Antiandrogens.- 8. Androgens in Prostate Cancer and Benign Prostatic Hypoplasia.- 9. The Expanded Poly-Q Length Within AR and AR Coregulator A1B1 And Their Clinical Implications.- 10. Androgen Receptor with Expanded Poly-Q Length in SBMA (Kennedy Disease).- 11. Androgen Insensivity Syndrome (Testicular Feminization).- 12. Androgens in Immunology and Autoimmune Diseases.- 13. Androgens in Penile Development, Penile Erection and Erectile Dysfunction.- 14. Androgens and the Androgen Receptor in Male Sex Development and Fertility.- 15. Androgens and Brain Function: Behavioral Perspectives.- 16. Androgens, Skeletal Homeostasis, and Osteoporosis.- 17. Androgens and Coronary Artery Disease.- 18. Androgen Therapy in Nonendocrine Illnesses.- 19. Androgens and Androgen Receptor in Dermatology.- 20. Androgen Deficiency and Abnormality in Women.

Über Autor(innen)

, Ph.D., is the George Hoyt Whipple Distinguished Professor at the University of Rochester.