Brioni / Decker | Pharmacological Treatment of Alzheimer's Disease | Buch | 978-0-471-16758-7 | sack.de

Buch, Englisch, 549 Seiten, Format (B × H): 161 mm x 240 mm, Gewicht: 1012 g

Brioni / Decker

Pharmacological Treatment of Alzheimer's Disease

Molecular and Neurobiological Foundations

Buch, Englisch, 549 Seiten, Format (B × H): 161 mm x 240 mm, Gewicht: 1012 g

ISBN: 978-0-471-16758-7
Verlag: Wiley


Geboten wird ein vollständiger, ausgewogener Überblick über die neuropharmakologischen Grundlagen von Therapeutika für die Alzheimer-Krankheit. Neueste Untersuchungen molekularer Strukturen und aktuelle klinische Daten werden mit der Verhaltens- und Erkenntnisforschung verknüpft und interpretiert.
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Weitere Infos & Material


I -
The Neurology of Cognition: Structure and Management of Multiple Memory Systems in Alzheimer's Disease;
Interaction of Neuromodulatory Systems Regulating Memory Storage;
Monoamine and Acetylcholine Influences on Higher Cognitive Functions in Nonhuman Primates with Relevance to the Treatment of Alzheimer's Disease;
Cortical Acetylcholine and Attention: Neuropharmacological and Cognitive Principles Directing Treatment Strategies for Cognitive Disorders;
Neuropsychological Features of Alzheimer's Disease;
II -
Neuropathological Features of Alzheimer's Disease;
Normal Brain Ageing and Alzheimer's Disease Pathology;
Recent Developments in the Genetics of Alzheimer's Disease;
Neurofibrillary Tangles in Alzheimer's Disease: Clinical and Pathological Implications;
Amyloid Cytoxicity and Alzheimer's Disease: Roles of Membrane Oxidation and Perturbed Ion Homeostasis;
The Role of Apolipoprotein E in Neurobiology and the Pathogenesis of Alzheimer's Disease;
Animal Models Relevant to Alzheimer's Disease;
III -
Alzheimer's Drug Discovery and Development: Alzheimer's Disease: An International Public Health Problem- Clinical Goals, Strategies and Outcomes;
Use of CSF-based Markers in the Diagnosis of Alzheimer's Disease;
Considerations for Clinical Trials in Alzheimer's Disease;
Cholinesterase Inhibition in the Treatment of Alzheimer's Disease: Further Evaluation of the Clinical Effects of Tucrine;
Development of Muscarinic Agonists for the Symptomatic Treatment of Alzheimer's Disease;
Neuronal Nicotinic Receptors: Potential Treatment for Alzheimer's Disease with Novel Cholinergic Channel Activators;
Neurotrophic Factors: Potential for Therapeutic Intervention in Alzheimer's Disease;
A Fundamental Role for Estrogens in Cognition and Neuroprotection;
Alzheimer's Disease: Prospects for Treatment in the Next Decade.

Partial table of contents:

NEUROBIOLOGY OF COGNITION.

Structure and Dynamics of Multiple Memory Systems in Alzheimer's Disease (R. Kesner & M. Ragozzino).

Monoamine and Acetylcholine Influences on Higher Cognitive Functions in Nonhuman Primates: Relevance to the Treatment of Alzheimer's Disease (A. Arnsten & C. van Dyck).

Neuropsychological Features of Alzheimer's Disease (D. Salmon).

MOLECULAR ASPECTS OF ALZHEIMER'S DISEASE.

Normal Brain Aging and Alzheimer's Disease Pathology (R. Grewal & C. Finch).

Neurofibrillary Tangles in Alzheimer's Disease: Clinical and Pathological Implications (C. Clark, et al.).

ALZHEIMER'S DRUG DISCOVERY AND DEVELOPMENT.

Use of CSF-Based Markers in the Diagnosis of Alzheimer's Disease (P. Seubert, et al.).

Development of Muscarinic Agonists for the Symptomatic Treatment of Alzheimer's Disease (J. Jaen & R. Schwarz).

Conceptual Issues in Research on Inflammation and Alzheimer's Disease (J. Rogers).

Index.


Jorge D. Brioni and Michael W. Decker are the authors of Pharmacological Treatment of Alzheimer's Disease: Molecular and Neurobiological Foundations, published by Wiley.


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