Discovery and Development of Anti-inflammatory Agents from Natural Products

Erscheinungsjahr 2019
ISBN: 978-0-12-816992-6
Verlag: Elsevier Science Publishing Co Inc

Buch, Englisch, 332 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 520 g

Reihe: Natural Product Drug Discovery

Discovery and Development of Anti-inflammatory Agents from Natural Products, the latest volume in the Natural Product Drug Discovery series, presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations, with this volume focusing on molecules of natural origin and their synthetic analogues that have the potential to act against the pathogens responsible for inflammatory diseases. All aspects of each are covered, including isolations and structure elucidations, in vitro and in vivo biological activity, synthetic optimization, investigations of pharmacodynamics and kinetics, and the structure-activity relationships of anti-inflammatory natural products.

Written by active researchers and leading experts, this book brings together an overview of current discoveries and trends in this field. It will be a valuable resource for researchers working to discover promising leads for the development of pharmaceuticals in the prevention and treatment of anti-inflammatory diseases.

Zielgruppe

Chemists, Biochemists, Synthetic chemists; Phytochemists; Medicinal chemists; Combinatorial Chemists; Pharmacologists

Autoren/Hrsg.

Brahmachari, Goutam

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Chemie Organische Chemie Biochemie

Inhaltsverzeichnis

1. Discovery and Development of Anti-Inflammatory Agents from Natural Products: An Overview 2. Curcumin: Current evidences of its therapeutic potential as a lead candidate for anti-inflammatory drugs: An overview 3. Anti-inflammatory efficacy of some potentially bio-active compounds against rheumatoid arthritis 4. Natural anti-inflammatory agents for the management of osteoarthritis 5. Portrait on synthesis of some potent anti-inflammatory natural products 6. Recent developments on the anti-inflammatory potential of sesquiterpene lactones and their semisynthetic analogs 7. Hesperetin and Naringenin: Protective Effects against Metabolic Syndrome-Associated Inflammation 8. Therapeutic implications of anti-inflammatory natural products in Alzheimer's disease 9. Anti-inflammatory effects of probiotics 10. 6-Gingerol: A Therapeutically Potent Lead Candidate in Anti-inflammatory Drug Discovery

Über Autor(innen)

Brahmachari, Goutam
Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then, he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master's in 1992, specializing in organic chemistry. After receiving his Ph.D. 1997 in chemistry from the same university, he joined his alma mater the next year and has been a full professor of chemistry since 2011. The research interests of Prof. Brahmachari's group include synthetic organic chemistry, green chemistry, natural products chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With more than 25 years of experience in teaching and research, he has produced over 260 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 27 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves several scientific bodies in India and abroad, and also many international journals as an editorial member. He has also been serving as co-editor-in-chief for Current Green Chemistry. Prof. Brahmachari is the founder series editor of the Elsevier Book Series 'Natural Product Drug Discovery'. Prof. Brahmachari is an elected fellow of the Royal Society of Chemistry and a recipient of the CRSI (Chemical Research Society of India) Bronze Medal-2021 (for his contribution to research in chemistry), Dr Basudev Banerjee Memorial Award-2021 (for his contribution to the field of chemical sciences) from the Indian Chemical Society, INSA (Indian National Science Academy) Teachers Award-2019, Dr Kalam Best Teaching Faculty Award-2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World Ranking of the Top 2% Scientists (Organic Chemistry Category) in 2020-23, the AD Scientific World Ranking of Scientists in 2022-2024, and as the Scholar GPS Highly Ranked Scholar-2024 (Lifetime, securing a position in the top 0.05% of all scholars worldwide).