Obesity

Epidemiology, Pathophysiology, and Prevention, Second Edition
2. New Auflage 2012
ISBN: 978-1-4398-5425-9
Verlag: Taylor & Francis Inc

Buch, Englisch, 1008 Seiten, Format (B × H): 184 mm x 260 mm, Gewicht: 1862 g

The World Health Organization (WHO) has declared obesity a global epidemic. Its prevalence has more than doubled since 1980, causing a myriad of health problems for children and adults. Obesity: Epidemiology, Pathophysiology, and Prevention, Second Edition explores the molecular mechanisms and pathophysiology leading to obesity and metabolic disorders. It examines the safety of obesity drugs and drug development strategies as well as the role of physical activity, nutrition, and nutraceutical supplements in obesity treatment and prevention.

With contributions from a cadre of internationally known experts, the book covers a spectrum of essential topics related to this widespread phenomenon, including:

The relationship between obesity and type 2 diabetes
The addiction mechanism related to refined foods as a significant factor in obesity
The correlation between obesity and environmental estrogens, endocrine disruption, cigarette smoking, and inflammatory response
The role of drug and chemical toxicities and genomic imprinting disorders in obesity
The safety and regulation of prescription and over-the-counter weight loss drugs
Various diets, the glycemic index, and the role of exercise in treating or preventing obesity
Controversy over effective vs. banned weight loss supplements
Childhood obesity and its prevention
Bariatric surgery for weight management and reversal of metabolic disorders

As the public has become more aware of the deadly adverse effects of obesity, numerous products and programs have targeted the overweight and obese population, many with dangerous side effects. It is essential that we develop strategic, therapeutic intervention supported by credible data. This volume is an ideal reference point for researchers looking for new avenues of inquiry and practicing medical professionals, clinical nutritionists, and dietitians seeking guidance for their patients.

Zielgruppe

Nutritionists, dietitians, nutrition scientists, obesity researchers, health practitioners, bariatric physicians and nurses, epidemiologists, researchers in supplement industries, pharmacists, food scientists, exercise physiologists, public health workers, and academic institutions and research institutions involved in studies of weight management and obesity.

Autoren/Hrsg.

Bagchi, Debasis

Preuss, Harry G.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Epidemiologie, Medizinische Statistik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Public Health, Gesundheitsmanagement, Gesundheitsökonomie, Gesundheitspolitik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Ernährungsmedizin, Diätetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Präventivmedizin, Gesundheitsförderung, Medizinisches Screening
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Essstörungen & Therapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Endokrinologie

Inhaltsverzeichnis

Introduction
Epidemiology of Obesity; G. Turconi and H. Cena
Epidemiology of Type 2 Diabetes and Obesity; K. Corley, M. S. Cabrera, J. C. Desmangles, C. Fernandez, and A. Chatterjee
Pathophysiology of Obesity
Global View on the Development of Noncommunicable Diseases; K.-H. Wagner and H. Brath
Evidence for Refined Food Addiction; J. R. Ifland, H. G. Preuss, M. T. Marcus, K. M. Rourke, W. C. Taylor, and M. Lerner
Disruption of Development by Environmental Estrogens; F. S. Vom Saal, B. L. Coe, B. M. Angle, and J. A. Taylor
Cigarette Smoking, Inflammation, and Obesity; S. K. Biswas, I. L. Megson, C. A. Shaw, and I. Rahman
Role of Neurotransmitters in Obesity Regulation; S. E. Ohia, C. A. Opere, M. Kulkarni, and Y. F. Njie-Mbye
Neurobiology of Obesity; N. Eikelis
Leptin as a Vasoactive Adipokine; A. Bouloumié, C. A. Curat, A. Miranville, K. Lolmède, and C. Sengenès
Leptin-Induced Inflammation; N.-Y. Song and Y.-J. Surh
Overview of Ghrelin, Appetite, and Energy Balance; R. Fernández-Fernández and M. Tena-Sempere
Molecular Genetics of Obesity Syndrome; R. S. Dwivedi, M. R. Wing, and D. S. Raj
Sleep and Obesity; M. A. Miller, and F. P. Cappuccio
Obesity and Degenerative Diseases
Oxidative Stress Status in Humans with Metabolic Syndrome; C.-Y. Chen and J. B. Blumberg
Obesity and Type 2 Diabetes; S. Yaturu and S. K. Jain
Inflammation: A Hallmark of Obesity in Conflict with Wound Healing; S. Roy and C. K. Sen
Angiogenesis-Targeted Redox-Based Therapeutics; S. Chatterjee, D. Bagchi, M. Bagchi, and C. K. Sen
Obese and Overweight: A New Sensitive Population for Drug and Chemical Toxicities?; G. B. Corcoran
Genomic Imprinting Disorders in Obesity; M. G. Butler
Novel Concept in Obesity Drug Development
Adipose Drug Targets for Obesity Treatment; O. Boss, L. Lehr, and J.-P. Giacobino
History and Regulation of Prescription and Over-the-Counter Weight Loss Drugs; S. M. Schwartz and D. M. Savastano
Safety of Obesity Drugs
Safety of Obesity Drugs; A. K. Gupta and F. L. Greenway
Historical Perspective, Efficacy of Current Drugs, and Future Directions in the Management of Obesity; B. Khandalavala and A. Chatterjee
Natural, Nutritional, and Physical Approaches of Weight Management
Essential Role of Exercise and Physical Activity in Weight Management; D. Blatt and C. L. Gostic
Role of Exercise in Diet and Weight Loss; W. J. Kraemer, C. Dunn-Lewis, and H.-Y. Luk
Role of Exercise in Weight Management and Other Health Benefits: Emphasis on Pedometer-Based Program; H. G. Preuss, D. Bagchi, and G. R. Kaats
Overview of Nutritional and Dietary Approaches for Weight Control; S. Agarwal
Gender Effects on Adiposity; S. Cvitkusic, D. J. Baer, and G. K. Harris
Beyond Obesity Prevention: Anti-Aging effect of Caloric Restriction; K. W. Saupe and J. D. Mulligan
Carbohydrate Digestion Inhibitors; J. K. Udani and M. L. Barrett
Vegetarian Diets in the Prevention and Treatment of Obesity; K. T. Knecht, H. T. Cale, H. T. Bui, D. K. Tran, and J. Sabaté
Atkins Paradigm; A. Robarge and B. W. Downs
Nature vs. Nurture: Role of Plant-Based Diet in Obesity Management; D. Ghosh
Glycemic Index; D. J. A. Jenkins, K. Srichaikul, A. Mirrahimi, L. S. A. Augustin, J. L. Sivenpiper, L. Chiavaroli, and C. W. C. Kendall
Chromium (III) in Promoting Weight Loss and Lean Body Mass; D. Bagchi, M. Bagchi, S. Zafra-Stone, and H. G. Preuss
An Overview on (-)-Hydroxycitric Acid in Weight Management; D. Bagchi, S. Zafra-Stone, M. Bagchi, and H. G. Preuss
Review of the Safety and Efficacy of Bitter Orange (Citrus aurantium) a

Über Autor(innen)

Bagchi, Debasis
Debasis Bagchi is a professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy in Texas and the Director of Innovation & Clinical Affairs at Iovate Health Sciences Research Inc., in Oakville, Canada. His research interests include free radicals, human diseases, carcinogenesis, pathophysiology, mechanistic aspects of cytoprotection by antioxidants, and regulatory pathways in obesity, diabetes, and gene expression. He has received funding from various institutions and agencies, including the U.S. Air Force Office of Scientific Research, Nebraska State Department of Health, Biomedical Research Support Grant from National Institutes of Health (NIH), National Cancer Institute (NCI), Health Future Foundation, The Procter & Gamble Company, and Abbott Laboratories. Dr. Bagchi received the Master of the American College of Nutrition Award in 2009. He has authored 287 peer- reviewed publications and 15 books.

Preuss, Harry G.
Harry G. Preuss is a tenured professor at Georgetown University (Washington, D.C.) in four departments—biochemistry, physiology, medicine, and pathology. His current research, both laboratory and clinical, centers on the use of dietary supplements and nutraceuticals to favorably influence or even prevent a variety of medical perturbations, especially those related to obesity, insulin resistance, and cardiovascular disorders. He has also researched the ability of essential oils and fats to overcome various infections, including those resistant to antibiotics. He recently won the coveted Charles E. Ragus Award of the American College of Nutrition (ACN) for publishing the best research paper in their journal for the year 2006 and the ACN Award for 2010 given to an outstanding senior investigator in nutrition.